I-oxymetazoline ne-xymetazoline yizinto zokwelapha ezakhiwe nge-vasoconstrictive, ngesisekelo sokuthi amaconsi namasprasi asemanzini akhiqizwa ukukhulula ukuvuvukala kwamagundane amancane. Lezi zidakamizwa zisetshenziselwa ikakhulukazi izifo zokuphefumula, zihambisana nokuxutshwa kwe-nasal , kanye ne-otitis. Cabangela ukuthi yini engcono ukuyisebenzisa-oxymetazoline noma i-xylometazoline, yiziphi umehluko nokufana kwazo.
Uyini umehluko phakathi kwe-oxymetazoline no-xylometazoline?
I-oxymetazoline ne-xylometazoline zakha izinto ezifanayo zeqembu le-imidazolin. Zithinta zombili izinhlobo ze-receptors zemithambo yegazi ezisemkhatsini we-mucosa wangasese (i-α1 ne-α2 receptors). Lokhu kunikeza umphumela wokwelashwa okusheshayo, okhulunywa ngokushesha futhi owanele.
Uma i-oxymetazoline isetshenziswa, ukuthuthukiswa kokuphefumula komzimba kuyabonakala amahora angaba ngu-10-12, futhi uma i-xylometazoline isetshenziswa, kancane kancane, cishe amahora angu-8. Kodwa-ke, umthelela onamandla kangaka nokusetshenziswa isikhathi eside kwalesi sidakamizwa kuholela ekulimaleni kwendwangu yamangcwaba, kuze kufike ku-atrophy. Ngakho-ke, kunconywa ukuba uwasebenzise ngokuqhubekayo izinsuku ezingekho kwezinsuku ezinhlanu ze-xylometazoline nezinsuku ezintathu ze-oxymetazoline.
Umehluko phakathi kwe-xylometazoline ne-oxymetazoline nawo ubukhulu be-withdrawal syndrome ngemuva kokuyeka ukusetshenziswa kwabo. Ngakho-ke, ukuwohloka komzimba ngemva kokuphelelwa ukwelashwa nge-oxymetazoline kuncane kakhulu kunokulandela i-xylometazoline. Ngaphezu kwalokho, i-xylometazoline iphikisana ngokweqile ekukhutheni, futhi i-oxymetazoline ivumelekile ukuthi isetshenziswe ngesikhathi sokubeletha komntwana emithweni encane ngaphansi kokuqondiswa udokotela.
Ukuphikisana okuvamile kwezidakamizwa yilokhu:
- isifo sikashukela mellitus;
- i-glaucoma yokuvala i-angle;
- I-pathologies ye-gland yegciwane;
- isifo sofuba;
- i-atrophic rhinitis .
Ngenxa yalokhu okushiwo ngenhla, kungaphetha ngokuthi ukulungiswa kwamanzi okusekelwe e-oxymetazoline kuyingozi. Kodwa-ke, igama lokugcina kufanele libe yilapho odokotela abaya khona kuphela, obala ukuthi izici zomzimba zesiguli kanye nobuhlungu be-pathology, angenza kahle.
Amalungiselelo asekelwe e-oxymetazoline ne-xylometazoline
Izidakamizwa ezivamile ngezinto ezisebenzayo xylometazoline yizi:
- I-Halazolin;
- I-Pharmazoline;
- Otrivin.
Ngesisekelo se-oxymetazoline, izidakamizwa ezinjalo zikhiqizwa:
- Knoxprey;
- Rinazolin;
- I-Nazivin.