I-glycated (noma i-glycosylated, i-HbA1c) i-hemoglobin iyinkhomba yezinto eziphilayo ezibonisa izinga lokushukela egazini lezinyanga ezintathu ezidlule. I-Hemoglobin iyiprotheni equkethwe amangqamuzana abomvu egazi. Ngokudonswa isikhathi eside kulawo maprotheni, bayazibopha ekomidini elibizwa ngokuthi i-hemoglobin glycated.
Thola ukuthi i-hemoglobin ene-glycated njengephesenti ye-hemoglobin ephelele egazini. Ephakeme izinga lokushukela, i-hemoglobin engaphezulu, ngokulandelanayo, iboshiwe, futhi kuphakanyiswe leli xabiso. Futhi ngokucabangela iqiniso lokuthi i-hemoglobin ayibopheli kanyekanye, ukuhlaziywa akubonisi izinga leshukela legazi okwamanje, kodwa inani elilinganiselwe izinyanga ezimbalwa, futhi enye yezindlela ezivame kakhulu zokuxilonga isifo sikashukela nesimo sangaphambi kwesifo sikashukela.
Umkhuba we-hemoglobin glycated egazini
Uhlobo olujwayelekile lomuntu onempilo lubhekwa njengobubanzi bama-4 kuya ku-6%, izinkomba ezivela ku-6.5 kuya ku-7.5% zingabonisa usongo wokuthuthukisa isifo sikashukela noma ukuntuleka kwensimbi emzimbeni, futhi amaphuzu angaphezu kuka-7.5% ngokuvamile abonisa ukuba khona kwesifo sikashukela .
Njengoba kubonakala, izindinganiso ezijwayelekile ze-hemoglobin glycated ngokuvamile ziphakeme kunendlela evamile yokuhlaziywa kwesimiso segazi (3.3 kuya 5.5 mmol / L okuzila ukudla). Lokhu kungenxa yokuthi izinga lokugcoba kwegazi kunoma yiliphi umuntu liguquguquka lonke usuku, futhi ngisho nangemva kokudla kungadlulela ku-7.3-7.8 mmol / l, futhi ngokwesilinganiso kungakapheli amahora angu-24 umuntu onempilo kufanele ahlale ngaphakathi 3.9-6.9 mmol / l.
Ngakho-ke, inkomba ye-hemoglobin ye-glycated ye-4% ihambisana noshukela wegazi we-3.9, no-6.5% kuya ku-7.2 mmol / l. Ezigulini ezinezinga elifanayo lokushukela kwegazi, inkomba ye-hemoglobin ye-glycated ingase ihluke, kufike ku-1%. Ukungqubuzana okunjalo kuvela ngoba ukwakhiwa kwalolu cwaningo lwezinto eziphilayo kungathonywa izifo, ukucindezeleka, ukungabi namacronutrients ethile (ikakhulukazi insimbi) emzimbeni. Kwabesifazane, ukuphambuka kwe-hemoglobin glycated kusuka evamile kungabonakala ekukhulelweni, ngenxa ye-anemia noma isifo sikashukela somama.
Indlela yokunciphisa izinga le-hemoglobin eli-glycated?
Uma izinga le-hemoglobin eline-glycated landa, lokhu kubonisa isifo esibi noma kungenzeka ukuthuthukiswa kwayo. Ngokuvame ukwanda kwesifo sikashukela, lapho amazinga kashukela ephakeme ephezulu egcinwa njalo. Ngaphansi kancane - ukungabi nalutho emzimbeni nase-anemia.
Isikhathi sokuphila samaseli abomvu asemayelana nezinyanga ezintathu, yilesi sizathu sesikhathi lapho ukuhlaziywa kwe-hemoglobin eglycated kubonisa izinga eliphakathi kweshukela egazini. Ngakho-ke, i-hemoglobin ene-glycated ayibonakali ukungafani okukodwa kwezinga leshukela legazi, kodwa ikhombisa isithombe esiphezulu futhi kusiza ukucacisa ukuthi ngabe izinga leshukela legazi lidlulile yini evamile
Ukuze ulungiselele lesi sibonakaliso, udinga ukuhola impilo enempilo, ulandele ukudla okunqunyiwe, uthathe imithi enqunyiwe noma wenze imijovo ye- insulin futhi uqaphe amazinga kashukela egazini.
Ngesifo sikashukela, isilinganiso se-hemoglobin esine-glycated esiphezulu kunabantu abanempilo, kanti isibalo sivunyelwe kuze kube ngu-7%. Uma isibonakaliso singaphezu kwezingu-7% ngenxa yokuhlaziywa, lokhu kubonisa ukuthi isifo sikashukela asikhokhiswa, okungaholela ekuthuthukiseni izinkinga ezinkulu.