Umsebenti wesimiso se-cardiovascular uhlolwe ngokulinganisa umfutho wegazi. Ngokwehlukana okuhlukile kwalesi sibonakaliso, isidakamizwa seCaptopril sinqunywe. In cardiology isetshenziswa kaningi, futhi ngisho nesisekelo sezikhathi zesikhathi eside zokwelashwa.
Naphezu kokusakazeka kwale mithi, akuzona zonke iziguli ezikwazi ukucindezeleka ukuthatha uCaptopril nokuthi zisebenza kanjani emzimbeni nhlobo.
Kunciphisa noma kwandisa ingcindezi yeCaptopril?
Isidakamizwa esichazwe sakhiwe ngesisekelo sensimbi esebenzayo yegama elifanayo. Ufakwe eqenjini le-ATP-angiotensin eliguqula i-enzyme inhibitors. Lokhu kusho ukuthi i-captopril ivimbela ukwakheka kwezinto ezikhethekile ezibangela ukumiswa kwe-lumen yemithwalo yegazi. Ngesikhathi esifanayo, isithako esisebenzayo sikhuthaza ukuqoqwa kwe-bradykinin. Le-enzyme ikhulisa ama-vascular gleams.
Ngakho-ke, lesi sidakamizwa sinomthelela omubi kakhulu, futhi kulula ukuqagela ukuthi yikuphi ukucindezela komzimba ukuthatha i-Captopril - yanda. Ngaphezu kwalokho, imithi iveza imiphumela elandelayo:
- Thuthukisa ukubekezelelana kwemisipha yenhliziyo kumthwalo;
- ukunciphisa ukuphikiswa kwamakhemikhali egazi kumanzi;
- ukwanda kwe-renal ne-coronary blood flow;
- ukunciphisa ngamandla ekukhiqizeni kwe-aldosterone ezinhlakeni eziyingozi;
- ukwanda komthamo womzuzu wenhliziyo;
- ukunciphisa kwengcindezi yegazi endaweni ye-aortic;
- ukujwayelekile kwemigomo yokucindezela kokushada emjikelezweni we-pulmonary (encane) wegazi nokujikeleza kwegazi;
- ukunciphisa kwe- platelet aggregation .
Ngokusetshenziswa kakhudlwana kwalesi sidakamizwa, ukunikezwa kwegazi ku-myocardium kuthuthukisiwe ngaphansi kwezimo zezinqubo zesimiso esibukhali, ubukhulu be-hypertrophy, kanye nokwanda kwamathambo ezindongeni ze-artery of type resistive, kunciphisa.
Iyiphi izinga le-high blood pressure elizosiza amaphilisi e-capsopril?
Isidakamizwa esivezwayo ngokuvamile sikhethwe ukulungiselela izifundo ezihlala isikhathi eside noma ezihlala njalo zokwelapha nokwelashwa kwesondlo.
Isidakamizwa sisebenza kahle kakhulu ezifweni ezibangelwa yi-hypertensive degree of degree to moderate, lapho ama-indices we-tonometer engadluli angu-179 ngo-109 mm Hg. Art. Kulesi simo, lesi sidakamizwa singasetshenziswa futhi sibe yi-monotherapy enokuvinjelwa kokungenwa kwamakhemikhali e-sodium emzimbeni.
Ukusetshenziswa kwe-captopril ngokucindezela okukhulu kakhulu, ngaphezu kuka-180 nge-110 mm Hg. kumele ukuthi kuhlanganiswe nokuphathwa kwe-thiazide diuretics (diuretics). Isilinganiso semithi eyisisekelo siyakhula kancane kancane kuze sifinyelele ekujuleni okuvunyelwe - 150 mg wezithako ezisebenzayo ngosuku.
Kungashiwo ukuthi lo muthi usiza kunoma yikuphi ukucindezela okwandisiwe, ikakhulukazi ngokuhambisana nezidakamizwa ezisekelayo.
Ngumuphi ukucindezela yizinkomba zokusetshenziswa kweCaptopril?
Ngenxa yalezi zici ezingenhla, le mithi elwa namagciwane iyasiza kokubili okunomusa nokulinganisela, futhi
Ngaphezu kwalesi sifo, i-captopril iboniswa ukwelashwa kwezifo ezilandelayo:
- i-infarction ye-myocardial ne-left ventricular ukungasebenzi, uma isimo sesiguli sizinzile;
- I-hypertension yenzeni;
- ukuhluleka kwenhliziyo okungapheliyo noma ukugcoba (ukuxilongwa kokuhlanganiswa okuyinkimbinkimbi);
- isifo sikashukela sohlobo lwe-1 ngesifo sofuzo soshukela, uma i-albinuria level ingaphansi kuka-30 mg / ngosuku;
- ukukhathazeka ngokwemvelo.