I-Triiodothyroxine noma i-T3 iyi-hormone ekhishwa yi-gland ye-gland ngesisekelo se-tetraiodothyroxine (T4), ngenxa yokungena kwayo. Ikhiqizwa ngevolumu elincane, kuphela i-10% kuphela, kodwa yiyona into esemqoka ephilayo ye-endocrine isitho.
Ngokuvamile ukuhlola imisebenzi ye-gland yegciwane kuyadingeka ukunquma i-T3 mahhala - yiliphi uhlobo lwe-hormone futhi lihloswe ngani, yazi abambalwa. Kodwa-ke, leli fomu lika-triiodothyroxine libhekwa njengento ebaluleke kunazo zonke ye-metabolism yamandla emzimbeni.
I-hormone ye-thyroid T3 isabela kanjani?
I-precursor yezinto ezicatshangelwayo yi-tetraiodothyroxine, equkethe ama-molecule angu-4 e-iodine. I-T4 yi-hormone esebenzayo, eyenziwa yi-gland yegciwane eningi (cishe 90%).
Ngemva kokuhlukaniswa kwe-molecule eyodwa ye-iodine esuka ku-tetraiodothyroxine, i-T3 yenziwa. Le hormone ingama-10 asebenzayo ngaphezu kwe-T4, inesibopho sezinhlelo zokusatshalaliswa kwamandla, ukuthuthukisa umsebenzi wezinzwa, kuhlanganise nomsebenzi wobuchopho. Eqinisweni, i-triiodothyroxine iyisisusa esiyinhloko kuzo zonke izinqubo ezibalulekile emzimbeni.
Uma i-T3 ingena egazini, libopha kuma-protein. Benza umsebenzi wokuthutha, behambisa i-hormone kulawo malungu nezicubu, lapho kunesidingo esiphuthumayo. I-triiodothyroxine eboshwe ekuhlaziyeni ibizwa ngokuthi i-generic.
Inani elincani le-hormone lihlala egazini elivinjelwe amaprotheni, yilokho i-T3 ikhululekile. Ukucutshungulwa kwalo kubhekwa njengento ebalulekile ekutadisheni umsebenzi we-thyroid, ngoba i-triiodothyroxine engabonakali iyasebenza kakhulu futhi ikhiqiza imiphumela echazwe ngenhla.
Khulula i-hormone ye-thyroid T3
Ama-laboratories ahlukene abeka imingcele yabo evamile yezinto ezibuzwayo. Baxhomeke endleleni yokubala ukuhlushwa kwayo, izingxenye zokulinganisa nokuzwela kwemishini esetshenzisiwe.
Ukuhlaziywa kwama-immunochemiluminescent anembile kakhulu, amanani achazwe aphakathi kuka 2.62 kuya ku-5.69 nmol / l. Uma kukhona imishini engacabangi kakhulu, umkhawulo ophezulu wendabuko ngokuvamile uboniswa phezulu, 5.77 nmol / l.
Ngenxa yalokho i-hormone T3 ekhululekile yanda?
Ukwehlukana kwamanani evamile avamile kuvame ukukhombisa izifo ezahlukene noma izimo zesikhashana zomzimba ezibangelwa ukwelashwa okuqondile.
Izizathu ezibalulekile zokukhulisa i-hormone T3 mahhala:
- ngokweqile kwesisindo somzimba esinconywayo;
- inkambo ye-hemodialysis esanda kuqedwa;
- ukungasebenzi kwe-thyroid (okwesikhashana) ngemva kokubeletha;
- i-myeloma inhlanganisela nokuhlushwa okuphezulu kwe-immunoglobulin G;
- subacute noma acute thyroiditis;
- isifo esingelapheki kwesibindi;
- i-nephrotic syndrome ekuthuthukiseni i-glomerulonephritis;
- Ukutheleleka nge-HIV;
- i-choriocarcinoma;
- hyperestrogenia;
- i-porphyria ;
- isakaza i-goiter enobuhlungu;
- ukwamukela ama-hormone e-thyroid, izinhlobonhlobo zokuvimbela umlomo, imethadone, i-cordarone.
Kuyadingeka ukuphuthuma ukubhekana ne-endocrinologist uma i-hormone T3 mahhala iphakanyiswa - ukwelashwa okuqalile ngokuhamba kwesikhathi, kuyosiza ekugwemeni izinkinga zezifo ezibekiwe, ukuvimbela ukukhula kwezimo eziphuzayo ezingathandeki kanye nemetastasis.
Kungani i-hormone T3 ikhululekile?
Ukuncipha kwenani le-tri-thirotoxin elingabonakali akuyona eyingozi njengokunyuka kwalo. Izizathu eziyinhloko zemiphumela enjalo
- ukungakwazi ukusebenza komsebenzi;
- ukugula ngengqondo;
- ukudla okuncane emaprotheni;
- i-hypothyroidism ;
- ukutakula ezifweni ezinzima;
- ukwelashwa nge-statins, anabolic, izidakamizwa eziphikisayo, izidakamizwa ze-antithyroid, i-steroids;
- ukwamukelwa kwamuva kwezindlela zomsakazo.