Imithi yanamuhla iyaqhubeka njalo. Isibonelo esicacile salokhu ukuphathwa kwe-photodynamic. Le ndlela yokwelapha iye yasungulwa isikhathi eside, kodwa isetshenziswe ngokusebenzayo kuphela eminyakeni embalwa edlule. Ngenxa yokusebenza kwayo, ukwelashwa kwe-photodynamic sekutholile uhlelo lokusebenza emagatsheni amaningi omuthi.
Uyini umehluko omkhulu kanye nezinzuzo ze-laser photodynamic therapy?
Isisekelo se-photodynamic therapy yi-photosensitizers. Le yimithi ekhethekile ezwela kakhulu ekukhanyeni. Ngenxa yethonya kubo ngabo ngosizo lwamagagasi e-laser ubude obuthile, umphumela odingekayo ufinyelelwe.
Kalula nje, i-drug-photosensitizer ifakwe emzimbeni. Zonke izindlela zanamuhla azizona ezinobuthi futhi zingakwazi ukuqoqa ngokushesha izicubu ezithintekayo. Emva kwalokho, isetshenziswa se-photodynamic therapy sisetshenziswa. Umthombo wemisebe ye-laser, evumela ukulawula ubude nokuqina kwamagagasi. Phakathi nokuxhumana ne-laser, i-photosensitizer ijabule, ukusabela kwe-photochemical kuqala, ngenxa yalokho ama-radicals amahhala akhiwa. Lezi zinsuku zinomthelela omubi kumaseli we-neoplasms, futhi zixazulula kancane kancane. Endaweni ye-tumor ngemuva kwenqubo, kusetshenzwa izicubu ezinempilo enempilo.
I-Photodynamic therapy iboniswa ngezinkinga ezinjalo:
- i-melanoma ;
- umdlavuza wesikhumba (i-squamous, basal cell, metatypic);
- izicubu eziphikisana nezinye izindlela zokwelapha;
- Ama-neoplasms angasebenzi (ngokuvamile atholakala ezindaweni ezinzima ukufinyelela).
Ngezinye izikhathi ukwelashwa kwe-photodynamic kuba yindlela kuphela yokwelapha isiguli. Yiqiniso, le ndlela ayithethi, kodwa imiphumela ebonisa ukuthi ifanelekile ngenhlonipho.
I-Photodynamic therapy ku-oncology
Ekuqaleni, le ndlela yasungulwa ikakhulukazi ukwelashwa komdlavuza. Ungakhuluma okuningi mayelana nezinzuzo zayo.
- Lena indlela engathintana ngayo yokwelashwa, ngokulandelana, amathuba okungena ekutheleleni emzimbeni awuncane.
- Ukuze uphulukise, ngezinye izikhathi inqubo eyodwa yanele.
- Ukususwa kwezicubu ezithathelwanayo kudlula ngokushesha, ngaphandle kwegazi, kungenabuhlungu.
- Ngemuva kokusebenza kwe-laser, azikho izibazi ezisele.
Ngo-oncology, i-PDT isetshenziselwa ukulawula ama-neoplasms wezesayizi nezindawo ezahlukene. Ama-Basaliomas yi-tumor ezwela kakhulu emisebeni ye-laser. Umthamo we-photosensitizer nokukhanya kwesiguli ngasinye kukhethwe ngamunye.