Ukuphulwa kombuso we-asidi-base, obonakala ngokweqile kwama-acid emzimbeni, kubizwa ngokuthi i-metabolic acidosis. Ukuhlukanisa phakathi kwe-acidosis ephindwe futhi engavumelekile. Esikhathini sokuqala, i-pH yegazi iseduze nomkhawulo ophansi wendabuko, futhi okwesibili - kukhona ukushiyeka okushiwo ku-asidi, lapho kudalwa khona amaprotheni, ukungabi nokukhiqizwa kwama-enzyme, ukubhujiswa kwamangqamuzana omzimba. Ukugeleza okulukhuni kwezinqubo ze-metabolic kungaholela ekufeni.
Izimbangela zeMetabolic Acidosis
Isizathu esiphuthumayo sokuthuthukiswa kwalesi sifundazwe siyaziwa - yi-oxydation yomzimba ngenxa ye-oksijini yindlala kanye nokungafaneleki kwe-acids eziphilayo (ukusebenza okungalungile kwamapayipi, izinso nezinye izitho zesistimu ye-excretory) Izimbalwa eziningi zidala ukushintsha kwesilinganiselo se-acid-base:
- ukungcola kwemvelo;
- indlela yokuphila yokuhlala;
- ukutholakala ngokwanele emoyeni omusha;
- imikhuba engafanele (ukubhema, utshwala, njll);
- ukudla okungenamkhawulo.
Kufanele kucaciswe ukugcina kulezi zici. Iqiniso liwukuthi ngokusekelwe egameni lokwephulwa, abanye bacabanga ukuthi i-acidification ibangela ukudla okune-acidic ukunambitha. Akunjalo. Ama-acids emzimbeni akhiwa ngenxa yokuwohloka kwamafutha, ama-hydrocarboni, izinhlobo ezithile zama-amino acid, njll. Izithelo kanye nemifino, kanye namafutha omquba aqukethe ama-anion awanciphisa ama-acid e-organic.
I-acidium e-acidiosis enamandla iyenzeka ngezimo ezesabekayo zomzimba ngenxa yokulimala kanzima, ubuthi , ukusetshenziswa kabi kotshwala, njll.
Izimpawu ze-Metabolic Acidosis
Izimpawu ze-acidosis yizi:
- isicanucanu, ukuhlanza:
- ukwehla kwamandla;
- i-palpitation;
- ukwanda kwengcindezi yegazi ;
- ukukhungatheka kwesimiso sezinzwa zomphakathi (ukudideka, ukudideka).
Kumele kuqashelwe ukuthi ngezinhlobo ezincane ze-acidosis, lezi zimpawu ziyasuswa. Ukuze uhlolwe ukwephulwa kwe-acid-base balance, lezi zifundo ezilandelayo zenziwa:
- ukuvuthwa kwemithi ukuthola i-pH;
- ukuhlaziywa kwegesi yokwakhiwa kwegazi lokugaya ukucacisa i-pH;
- Ukuhlaziywa kwegazi elibangelwa igazi lokuba khona kwama-electrolyte serum.
Ukwelashwa kwe-metabolic acidosis
Ochwepheshe bagcizelela: ukwelashwa kwe-acidosis kufanele kwenziwe kwinkimbinkimbi. Uma kukhona izifo ezingapheli kuyadingeka ukuthi uphathe ukwelashwa kwesifo esiwumgogodla esibangele ukuguqula ibhalansi ye-acid-base emzimbeni wesiguli. Uma kwenzeka ukuthuthukiswa kwe-acute acidosis, kunesidingo esihlosiwe sokunciphisa ithonya lezinto ezilimazayo, isibonelo, uma ubuthi, kubalulekile ukugeza isisu sesiguli. Ngokwebuthe obukhulu, i-dialysis ingenziwa. Uma kwenzeka ukuphefumula kokuphefumula, isibonelo, ngenxa yokuhlukumezeka okukhulu, umoya wokuvuthwa owenziwe umisiwe.
Ukuze kulungiswe i-acidosis i-acidosis, i-fluid intravenous iboniswa. Ngezimo ezinzima, amalungiselelo e-sodium bicarbonate anqunyelwe ukuphakamisa izinga le-pH ejwayelekile futhi ephakeme. I-bicarbonate ye-sodium ingeziwe kwizixazululo ze-chloride ye-sodium noma i-glucose ngamanani athile, okuxhomeke ekuphuleni kwemigomo yegazi. Imikhawulo ekudleni kwe-sodium ingafinyelelwa ngosizo lwe-Trisamine ye-diuretic. Lapho kutholakala i-pathologies ohlelweni lwe-broncho-pulmonary, i-diabetes mellitus noma i-rickets, i-Dimephosphonum ingasetshenziswa.
Ukunakwa sicela! Ukusetshenziswa kwemithi ye-anti-acidi yokwelapha kufanele kwenzeke ngaphansi kokuqondiswa kukadokotela oya khona, oqapha ngokucophelela ukuguqulwa kwama-asidi nama-alkali izinkomba ekuhlaziyeni kwesiguli.