Sekuyisikhathi eside, ukuthola ukuthi kukhona yini izifo zesifo sofuba emzimbeni wengane, ukusabela kukaMantoux kwasetshenziswa. Kodwa namuhla le ndlela ishintshwe ukuhlolwa kwe-quantiferon. Lena yindlela yokucwaninga yendawo yonke, engafaneleki kuphela iziguli ezincane. Kubuye kubalulekile kubantu abadala. Futhi uma kuqhathaniswa ne-Mantou yokusabela inezinzuzo eziningi kakhulu.
Kungani ukuhlolwa kwe-quantiferon yesifo sofuba kufakwe kakhulu kuneMantoux?
Ukukhathazeka okuyinhloko kweMantoux ukuthi le ndlela ibuhlungu kokubili izifo ze-TB nezifo zesifo sofuba. Ngenxa yalokhu, ukusabela kaningi kunganika umphumela omuhle wamanga. Uma ukholwa izibalo, kusukela kumaphesenti angu-50 ukuya ku-70 kuwo wonke umphumela wokuhlola awuthembekileki.
Yingakho esikhundleni seMantoux namuhla ziqhubeka nokuhlola i-quantiferon. Iqhutshwa ngokusho kobuchwepheshe besimanje, okuvumela ukugwema ukuthola imiphumela yamanga.
Ngaphezu kwalokho, i-Mantoux kanye nokunye okunye - i-Diaskintest - kunezinkomba eziningi. Ngeke ukwazi ukusebenzisa lezi zindlela zokuphenya lapho:
- ukungavumelani ngabanye ku-tuberculin;
- izifo eziwumshayabhuqe;
- ukutholakala kwezifo ezithathelwanayo nezifo ezingenasifo ezithathelwanayo;
- izifo zesikhumba;
- ukukhushulwa kwezimo ezivuthayo.
Izinkomba zokuhlolwa kwe-quantiferon
Isivivinyo esilinganiselwe sibucayi kakhulu futhi siqondile kakhulu. Isekelwe ekutholeni kwegazi lesiguli sezinto ezikhethekile ezingabonakala kuphela kwi-mycobacteria egciwane. I-Interferon i-IFN-y - into efanayo - ikhishwa ngamaseli e-T azwelayo.
Umphumela wocwaningo kwiziguli ezinempilo enhle, otheleleke nge-agent causative yesifo sofuba noma ukugonywa nge-BCG kuyoba yinto embi.
Uma uhlolo lwe-quantiferon luhlolo lwe-homo, luzobonisa umphumela omuhle, khona-ke lowo muntu uphethwe ngokunembile. Ukwesaba, uma uthola impendulo enhle, ngaso leso sikhathi akudingekile. Ubukhona obukhona emzimbeni we- pathogen wesifo sofuba akusho okwamanje isifo. Kungenzeka ukuthi umuntu ungumane othwala isifo. Ukunquma ukuthi ukuthuthukisa izifo eziphilayo, ukuhlolwa kwezikhumba zendabuko kuzosiza kanjani.
Isivivinyo se-quantiferon senzelwe:
- ukutholakala kokutheleleka kwesifo sofuba esifushane;
- ukuhlolwa kwabokufika;
- ukuxilongwa ngokungafani kwezifo ezingabangwa yi-mycobacterium isifo sofuba.
Okokuqala, ukuhlolwa kuqhutshwa iziguli ezisengozini:
- kusanda kuxhumana nabantu abanegciwane;
- ngubani owafakelwa ukufakelwa kwamaphaphu;
- ukuhlukunyezwa kwamaphaphu;
- Ukwelashwa nge-HIV;
- i-immunosuppressive therapy;
- ukuphethwe yisifo sikashukela, i-lymphomas, i-leukemia, ukwehluleka kwezinso noma izifo ezihlukahlukene ezizimele ;
- enesisindo esikhulu somzimba.
Izinzuzo zesilingo se-quantiferon
Imiphumela enokwethenjelwa nephezulu kakhulu yokuhlola kwe-quantiferon ayiyona inzuzo enkulu. Ngokungafani namasampuli asikisela ukusungulwa kwe-tuberculin, lokhu kuhlolwa kwenziwa "nge-vitro". Okusho ukuthi konke okudingwa isiguli ukunikela ngegazi bese ulinde umphumela. Ngenkathi ngemuva kweMantoux ne-Diaskintest, izindawo zokugcoba kufanele zihlolwe ngokucophelela futhi zigcinwe.
Ngaphezu kwalokho, ukuhlola kwe-quantiferon akunakho ukuphikisana, akukho ukulinganiselwa, akukho ukusabela okubi. Eqinisweni, lolu cwaningo luhlolo oluvame kakhulu lwegazi. Kufanele unikezwe esiswini esingenalutho okungenani amahora ayisishiyagalombili ngemuva kokudla kokugcina.