I-Thrombophilia ingukuphazamiseka kwesimo se-circulatory system, futhi ivela ekuguquleni kwemvelo ekubunjweni nasezindlini zegazi. Lesi sifo siholela kaningi ku-thromboembolism yemikhumbi enamandla, i-thrombosis yezindawo ezihlukile. Iningi labo bonke abantu bangakwazi ukuthola izifo ngemuva kokuhlinzwa, ngesikhathi sokukhulelwa, ngenxa yokudlulela ngokomzimba noma ukuhlukunyezwa. Uma usolwa ngokuthi i-tobobylia, udinga ukuhlolwa kwegazi kusuka emthanjeni futhi, njengokujwayelekile, esithombeni esingenalutho.
Yini ebangela i-thrombophilia?
Lesi sifo singaba nomlingiswa otholakele, obonakala ezingalungweni ohlelweni lwegazi lokugcoba noma ekuguleni kwamaseli. Futhi futhi imbangela ye-thrombophilia ingaba neoplasms ezimbi.
Kodwa-ke, ukuhlaziywa kwe-genetic thrombophilia kuze kube ngamacala angu-50% kunikeza umphumela omuhle. Lokhu kubonisa ukuthi ifa elihle kakhulu ekuthuthukiseni i- thrombosis ezigulini eziningi. I-pathology enjalo ingabangelwa ukuphazamiseka kwezakhi zofuzo kanye nokuguqulwa kwegazi kuhlelo lwe-coagulation ne-anticoagulation.
Kuyini ukuhlaziywa kwe-thrombophilia?
Kuze kube manje, ulwazi oluningi kakhulu luhlolo lwegazi lwe-thrombophilia. Ngalesi sifo, ukuhlolwa kwegazi kubonisa inani elikhuphukile lamaplatelet namaseli abomvu egazi. Umthamo we-erythrocyte ukwanda ngokuqondene negazi legazi.
Izinga legazi lithathwa yizinga lempahla, okufakazela ekubhujisweni kwe-thrombi, ebizwa ngokuthi i-D-dimer. Nge-thrombophilia, inani lalo liyakhula.
Ukuhlolwa kwemisebenzi ye-clothting yegazi kwenziwa ngenxa yokuhlaziywa okunquma i-APTT (isikhathi esithathiwe sesikhathi se-thromboplastin). Lesi sifo sibonakala ukwehla ku-APTT.
Ukulungiswa okukhethekile kokuhlaziywa kwe-thrombophilia yezofuzo akudingekile, isampuli segazi senziwa kwimodi evamile kanye nokuphila okuvamile kwesiguli.