I-Mildronate ngumkhiqizo wezokwelapha othuthukisa umzimba kanye nokukhuthaza ukunikezwa amandla kwamathambo. Kunamafomu amabili okukhululwa: ama-capsules nesisombululo se-injection ku-ampoules.
Indlela yokusebenzisa i-mildronate ixhomeke kulesi sifo nokuyinkimbinkimbi yayo. Isidakamizwa senziwa ngomlomo, nge-intravenously, nge-intramuscularly futhi nge-parabulbarically (ngaphakathi kweso).
Indlela yokwenza izinto ezincane
Indlela yokwenza i-Mildronate ukuhlinzeka ngokuvikelwa nokunikezwa kwamandla amangqamuzana ahlukahlukene omzimba. Futhi, izidakamizwa zivimbela ukuqoqwa kwemikhiqizo enobuthi ephakathi komzimba emzimbeni, evikela amangqamuzana emonakalweni. Ngaphezu kwalokho, i-mildronate iyanciphisa isilinganiso se-oxidation yamanoni amaningi, ngaleyo ndlela yenza kube lula ukusebenzisa uhlelo oluthile lwamandla. Okusemqoka kwalesi simiso ku-oxidation ye-glucose, futhi i-glucose iyaziwa ukusebenzisa i-oksijini ngokuphumelela kakhulu ekuhlanganisweni kwe-adenosine triphosphate (ATP).
Ukulungiswa kwemvelo: izinkomba zokusetshenziswa
Uhlu lwezifo lapho i-mildronate enqunywe khona likhulu kakhulu, okuyinhloko yilezi:
- ukuhluleka kwenhliziyo engapheli;
- i-angina pectoris, i- infarction ye-myocardial , ischemic disease;
- isifo sikashukela, i-osteochondrosis yesifunda somlomo wesibeletho, kanye nanoma yiziphi ezinye izimo lapho ukujikeleza kwegazi ebuchosheni kuphazamiseka khona;
- ngokudakwa ngokweqile - ukuhoxiswa kwesifo;
- ukwehla ngokusebenza kahle;
- ukuxoshwa kwemvelo yengqondo nomzimba, isibonelo, kubadlali;
- ekwelapheni imivimbo ehlangene nezinye izidakamizwa;
- i-cardiomyopathy, ngenxa yezinkinga ze-hormonal (ukusetshenziswa kwesikhathi eside kwe-prednisolone, ukuyeka esikhathini sokuqala)
- ukubola kwesifo se-retina esweni.
Uhlu olugcwele lwezinkomba lufakwe kwisichasiselo esiya kumuthi.
Kanye nobufakazi, udinga ukusho amagama ambalwa mayelana nokuphikisana. Lokhu kufaka:
- ukungezwani komuthi nezidakamizwa zayo;
- ukunyuka kwengcindezi yokunyuka;
- izicubu ezingenakudliwa;
- ukwephula ukuphuma okuvamile kwegazi elivela emcimbini.
I-Mildronate kubadlali
Ngenxa yezinto umkhiqizo onikezwe wona, kusetshenziswa kakhulu ezemidlalo.
I-Mildronate ngempumelelo isiza ukubhekana nabagijimi abanezinhlanzi, ngezinye izikhathi ezingavumelekile, kokubili ngokomzimba nangokwengqondo. Lo mphumela utholakala ngokubheka amandla omzimba okusebenzisa imithombo yawo yemvelo ngokulinganayo. Lokhu kungukuthi, umphumela we-mildronate wezidakamizwa uhlose ukuqinisekisa ukuthi umzimba ungakwazi, ngokushesha ngangokunokwenzeka futhi ngokushesha uvumelane nezimo ezicindezelayo, eziyimithwalo yemvelo, yengqondo nengokwengqondo.
Ngaphezu kokuzivumelanisa nezimo, i-Mildronate ibuye ibuyele ekuvuseleleni okusheshayo, ngakho-ke abameleli bezemidlalo eziningi futhi abahlukahlukene baye basebenzisa lesi sidakamizwa isikhathi eside ngesikhathi sokulungiselela nokuncintisana.
Kwabadlali, indlela ephumelela kakhulu yokuthatha i-mildronate yi-15-20 mg yesidakamizwa nge kilogram yesisindo isigamu sehora ngaphambi kokuqeqeshwa. Ubude benkambo buvela ezinyangeni eziyi-1.5 kuya kwezingu-3, bese uthatha ikhefu, ukuze unganciphisi ukwelashwa.
I-Mildronate ayiyona i-doping, njengoba ingakhulumi
I-Mildronate yokulahlekelwa isisindo
I-Mildronate i-analog ye-carnitine futhi ivuselela kakhulu izinqubo ze-metabolic. Khuluma ngomuthi njengendlela emele yokulahlekelwa isisindo akudingekile. Indima yakhe ekunciphiseni isisindo kuphela ngenxa yokuthuthukisa ukusebenza kwezemidlalo nokuzivumelanisa ngokushesha nomthwalo. Okusho ukuthi ukusebenzisa i-mildronate kunganciphisa isisindo, kodwa kuphela ngesikhathi sokuzikhandla okukhulu ngokomzimba.