Njengoba uDufaston manje esetshenziselwa kakhulu ukwelashwa kwezifo ezihlukahlukene kanye nezimo ze-pathological ezihambisana nokungalingani kwe-hormone, abesifazane banombuzo ozwakalayo wokuthi lesi sidakamizwa sinama-hormonal nayo yonke imiphumela elandelayo. Yilokho, ingabe inemiphumela emibi yezidakamizwa ezisekelwe kumahomoni.
Ukuze uphendule umbuzo wokuthi amaphilisi e-Dufaston angama-hormonal noma cha, kubalulekile ukwazi ukuthi iyiphi into esebenzayo esezingeni layo.
Into esebenzayo
Into esemqoka yeDufaston yi-dydrogesterone, eseduze ne-progesterone yemvelo. I-substantetic synthetic for progesterone, kodwa ayiveli ku-hormone yesilisa, echaza ukuthi kungani ingenayo i-anabolic, i-androgenic, i-estrogenic ne-thermogenic imiphumela ephawulekayo kwezidakamizwa eziningi ezisekelwe kumahomoni okwenziwa.
Kule ndaba, lesi sidakamizwa sinemiphumela emibi kakhulu. U-Dufaston usiza ukuvimbela ukuthuthukiswa kwezicubu ze-endometrial, engenayo umphumela wokukhulelwa, akuphazamisi umjikelezo wesimiso. Ngesikhathi sokuthatha izidakamizwa, ukukhulelwa kungenzeka. Ngokuhluleka kwe-hormone, i-Duphaston isiza ukuqinisa umjikelezo wokuphela kokuya esikhathini futhi ihlinzeke ngokuntuleka kwe-progesterone ye-hormone.
Ukungafani
Kodwa, naphezu kwazo zonke izinzuzo ezitholakalayo kulolu hlelo, kusengumuthi we-hormonal, okufanele usetshenziswe ngokucophelela okukhulu. Ukuqokwa kukaDufaston ngaphandle kokuhlola ngokucophelela, "uma kwenzeka" kungamukeleki. Phela, ngemuva kokungenelela okunjalo ohlelweni lokuzala, ukuhluleka kwamahomoni kungase kwenzeke. Ngakho-ke, ukusetshenziswa kukaDufaston kufanele kulungiswe futhi ngemuva kokuba kutholakale ukuthi kutholakala yini.
Isidakamizwa singabhalwa ukwelashwa kwezifo ezifana ne-endometriosis, ukungasebenzi, i-dysmenorrhea, i-premenstrual syndrome, i-amenorrhea, ukuphuma kwamagciwane okungasebenzi kahle , umjikelezo ongavamile. Kufanele kukhunjulwe ukuthi naphezu kokuthi imfundo ibhekisela ekusebenziseni uDufaston ngesikhathi sokukhulelwa, akubekho izifundo ezinokwethenjelwa ngokuphathelene nomphumela wokuthatha lesi sidakamizwa emntwaneni.
Ungathathi izidakamizwa futhi ungaboni ukungavumelani ku-dydrogesterone, i-Rotor ne-Dabin-Johnson syndromes.