I-creatinine idonswa izinso futhi iyisiqephu sokugcina samaprotheni umzimba. Ukwazi inani lalo mzimba emzimbeni, ungakwazi ukwahlulela isimo sezinso, ukusebenza kwazo. Kukhona njalo isizathu sokukhulisa nokunciphisa i-creatinine. Ngokuvamile ukuphambuka kwezinga lendaba okuvela kumkhuba kuyisibonakaliso sezifo ezihlukahlukene kanye nezinguquko ze-pathological.
Izimbangela zokunciphisa i-creatinine egazini
Ochwepheshe baye basungula uhlaka olukhethekile. Ngakho-ke, isibonelo, uma igazi liqukethe u-44 kuya ku-80 μmol / L we-creatinine, lokhu kubhekwa njengokujwayelekile. Ukungafani okuvela kumkhuba kubonakala njalo. Kodwa ezimweni eziningi, ochwepheshe kufanele babhekane nokwanda kwenani lendaba.
Ukunciphisa i-creatinine akuyona into engavamile. Lesi simo siboniswa ukuthi imetabolism kanye namaprotheni emisebentini iphazamiseka emzimbeni. Futhi lokhu, kubhekene nokunciphisa amandla omzimba womzimba, okungaba nemiphumela engathandeki kakhulu.
Izinto ezinjalo zingasiza ekunciphiseni ku-creatinine:
- izifo ezingapheliyo;
- indlala;
- izifo ze-muscle eziholela ekudleni kwabo;
- ukwehla okubukhali emzimbeni womuntu;
- izinkinga emsebenzini wezinso;
- i-rhabdomyolysis;
- izicubu ezimbi;
- ukuphelelwa amanzi ;
- ukulimala kwemisipha nezicubu ezungezile;
- ukuntuleka kwe-hormone ye-antidiuretic emzimbeni;
- ukuhluleka kwenhliziyo ;
- i-cirrhosis nezinye izifo zesibindi;
- i-cachexia ebangelwa indlala nezifo.
Ngokuvamile, ukunciphisa i-creatinine kutholakala ekuhlolweni kwegazi kwabesifazane abakhulelwe. Ikakhulukazi phakathi nenyanga yokuqala yokukhulelwa. Thuthukisa i-hypocreatinemia nokusetshenziswa kwe-glucocorticoids. Ngezinye izikhathi umzimba uphelelwe ngenxa yokungafani phakathi kwemithwalo yemvelo etholakalayo nokudla okunomsoco, okuyinto ethinteka ikakhulukazi abagijimi bamantombazane.