Umzimba womuntu wuhlelo oluyingqayizivele, oluyinkimbinkimbi. Naphezu komlando weminyaka eminingi wemithi, kuze kube manje, zonke izinsiza kanye namakhono omzimba womuntu azange zifundwe kahle. Ama-hormone enye yezindlela ezinamandla kakhulu zokuzilawula komzimba, futhi kulesi sihloko sizokhuluma ngomunye wabo - androstenedione. Ngokuqondile, mayelana nalokho okuboniswa izinga eliphezulu le-androstenedione, ukuthi unganciphisa kanjani i-androstenedione, nokuthi ngabe kuyadingeka yini ukhathazeke uma ukuhlolwa kwelabhoratri kubonise ukuthi i-hormone androstenedione iphakanyisiwe kuwe.
Iyini i-Androstenedione enesibopho?
I-Androstenedione yi-hormone ye-adrenals ne-gonads. Ikhishwa emzimbeni womabili wesilisa nowesifazane. Kuyinto engavumelani ukuxhunyaniswa nokuthuthukiswa kwama-hormone wesilisa nowesifazane, ikakhulukazi i-estrogen ne-testosterone. Inani elanele le hormone egazini livumela isibindi nesishukela ukukhiqiza ama-hormone ocansi.
Izinga le-androstenedione liqala ukuphakama ngokuphawulekayo kusukela eminyakeni engu-7-8. Ngemva kokufinyelela kumuntu oneminyaka engu-30 ubudala, ukuthuthukiswa kwaleli hormone kuyaqala kancane kancane.
I-Androstenedione: okuvamile kubantu besifazane namadoda
Izinga elivamile le-androstenedione egazini, kuye ngokuthi iminyaka yomuntu:
- izingane ezinsukwini ezingu-1-7 emva kokuzalwa - 20-290 ng / 100ml;
- Izinsana (izinyanga 1-12) - 6-68 ng / 100ml;
- izingane ezineminyaka engu-1-10 iminyaka-8-50 ng / 100ml;
- intsha (iminyaka engu-10-17) - 8-240 Ng / 100ml;
- amadoda - 75-205 Ng / 100ml;
- abesifazane - 85-275 Ng / 100ml.
Ukuhlukana okuphawulekayo kusuka ezingeni elijwayelekile le-androstenedione kungabonwa ngokudla kwezidakamizwa ze-hormonal, izicubu ze-etiologies ehlukahlukene kanye nezifo eziningana.
Androstenedion yaphakamisa: izimbangela
Izimbangela zamazinga okwandiswa kwe-androstenedione ingaba yinkinga emisebenzini ye-adrenal kanye / noma ye-ovarian. Ngokuvamile, ukwanda kwe-androstenedione kubonisa izifo ezinjalo:
- i-polycystic ovary;
- i-hyperplasia ye-cortex ye-adrenal;
- i-Itenko-Cushing syndrome;
- i-osteoporosis yesifazane;
- i-hypertecosis yama-ovaries;
- izicubu ze-ovarian zemvelaphi ehlukahlukene nezinye izifo.
Izinga eliphezulu le-androstenedione liyabonakala ngokungabikho kwama-ovari noma i-cortex ye-adrenal.
Ngokuya ngesikhathi sosuku, isigaba sokujikeleza kokuya esikhathini, i-androstendione level ihlukile. Amanani aphezulu ahlonishwa emahoreni asekuseni, futhi phakathi nesikhathi sokuya esikhathini kwabesifazane. Ngesikhathi sokukhulelwa, izinga le-hormone libuye landa.
I-Androstenedione iphakanyisiwe: izimpawu
Uma i-androstenedione yabesifazane iphakanyisiwe, ngokuvamile kuvame ukulahlekelwa izinwele ngokweqile (i-hirsutism), i-syndrome evuselelayo. Ukwanda kwezinga le-hormone kungabangela nokukhulelwa kwasekuseni, ukuphuma kwegazi, izinhlobonhlobo zezifo ezingasebenzi ekusebenzeni komzimba ngokulandelana kokungalingani kwe-hormonal jikelele.
Kukholelwa ukuthi ukwanda kwe-androstenedione kuholela ekukhuphukeni okusheshayo emzimbeni we-muscle, yingakho le hormone namalungiselelo aqukethe ngayo athandwa kakhulu phakathi kwabakhi bomzimba, nakuba kungenayo umphumela we-anabolic. Okwamanje, ukulimala kokusetshenziswa okungalawuleki kwezidakamizwa ezinjalo ngezikhathi ezithile kudlulela umphumela omuhle wokusetshenziswa kwayo - ukukhanya, ukukhulisa i-prostate, ukuhlukumeza komzimba (isibonelo, ukukhula kwebele emadodeni), izinwele ezithintekayo emzimbeni - okude kakhulu ohlwini oluphelele lwemiphumela yalo ukwamukelwa okungalawulwa.
Androstenedione ephakeme: ukwelashwa
Uma izinga le-androstenedione liphakanyisiwe kwabesifazane, ukwelashwa kuvame ukudingeka. Ukuze uhlolisise futhi ubeke ukwelashwa okwanele, udinga uxhumane ne-endocrinologist ne-gynecologist (yabesifazane) noma i-androlog (yamadoda).
Okuvame ukusetshenziswa kakhulu: i-dexamethasone, i-clomiphene, izakhi zokubeletha ezihlukahlukene ze-hormonal. Izinqubo zokwelapha, uhlu lwezidakamizwa nezindlela zokwelapha ziyahlukahluka kuye ngezimbangela kanye nemvelo yenkinga, ukutholakala kwezifo ezihambisanayo, ubudala nobujamo obujwayelekile besiguli. Ukuzitholela akuvunyelwe ngokuphelele. Zonke izidakamizwa ze-hormonal kufanele zibekwe kuphela ochwepheshe abaqeqeshiwe.