Lapho isifo senhliziyo sivame ukushiwo amaphilisi e-Panangin, ubufakazi bokuthola ukuthi sizocabangisisa ngezansi ngokuningiliziwe. Inkampani uGedeon Richter igcina i-patent yokulungiselela lo muthi, nakuba kunezindlela ezifanayo ezishibhile zomuthi.
Ukwakhiwa kwemithi
Isidakamizwa sine-potassium asparaginate hemihydrate kanye ne-magnesium asparaginate tetrahydrate. Lezi zinto ezisebenzayo ziwumthombo we-i-potassium ne-i-magnesium ions.
Njengoba izingxenye ezisizayo ekulungiseleleni zisetshenziswa:
- i-silicon dioxide colloidal;
- i-talc;
- i-povidone;
- isitashi samabele kanye namazambane isitashi;
- i-magnesium stearate.
Amaphilisi ane-coating evikelayo, ehlanganisa ama-macrogol 6000, titanium dioxide, talc, methacrylic acid copolymer.
Uma kunezibonakaliso eziqondile zokusetshenziswa, i-Panangin isetshenziselwa ukujova: isidakamizwa sithengiswa ngesimo sesisombululo sokuphatha okungaphakathi. Iqukethe i-potassium aspartate ne-magnesium asparaginate, namanzi omjovo njengengxenye eyisizayo.
Kungani usebenzisa i-Panangin?
Ama-cations of magnesium ne-potassium atholakala emaseli omzimba, aphethwe izinqubo zokuqhekeka kwemisipha kanye nokukhiqizwa kwama-enzyme athile. Isilinganiso sazo nge-sodium ion sithinta umsebenzi we-myocardium. Uma okuqukethwe kwe-potassium kumangqamuzana kungenele, kungaholela ekuthuthukiseni i-arrhythmia (ukuphazamiseka kwengqondo yenhliziyo), ukucindezeleka komzimba (ukucindezeleka okuphansi), i- tachycardia (ukushaya kwenhliziyo okusheshayo) nokuwohloka kokuthengiswa kwe-myocardial ngokuvamile.
I-magnesium inciphisa izinga lenhliziyo, ivimbela ischemia ye-myocardium futhi inciphise isidingo sayo se-oksijeni. Odokotela bathole ukuthi kahle isisu se-sulfurine sibekezelele i-magnesium ne-i-potassium ions, okufaka isandla ekungeneni kwabo emangqeleni futhi ngaleyo ndlela kuthuthukise umsebenzi wenhliziyo kanye nezinqubo ze-metabolic ngokujwayelekile.
Yini esiza iPanangin?
Ngokweziqondiso, izinkomba zokusetshenziswa kwePanangin zimi kanje:
- izinkinga ze-heart rhythm ngenxa yokungalingani kwe-electrolyte;
- hypokalemia (ukuntuleka kwe-potassium emzimbeni);
- ukuphazamiseka kwesigqi ngenxa yokudlula ngokweqile kwemithi evela ku-digitalis isithombo (digitalis);
- ukungakwazi ukusebenza komzimba;
- ukuphazamiseka kwemithi ye-myocardium, ehambisana nokunikezwa okwanele komoya;
- ukuphulwa okwakusanda kuthuthukiswa kwesigqi se-ventricles yenhliziyo;
- i-friction fibrillation paroxysms.
Indlela yokusebenza
Isidakamizwa sinconywa ukuba sithathe emva kokudla, ngaphandle kwalokho imvelo ese-acidic yesisu izonciphisa ukusebenza kwayo. Bhala amaphilisi amabili, okudingayo ukuphuza kathathu ngosuku.
Ngezinye izikhathi izinkomba zokusetshenziswa kwePanangin zidinga ukulawulwa kwezidakamizwa ezithintekayo zomuthi. Inqubo iphindwa emva kwamahora angu-4-6. Ngesikhathi, ungakwazi ukuthulula okungaphezu kwama-ampoules angu-2.
Ukufana kwezidakamizwa
Kumele kuqashelwe ukuthi iPanangin, izinkomba zokusetshenziswa kwazo ezinikezwe ngenhla, zinokulungiswa kwe-analog - Asparkam. Zifana ngokuphelele ekubunjweni kwamakhemikhali, kodwa i-Panangin, ukuba imithi yokuqala kanye neliphikisiwe, ibiza ngaphezulu. Kukholelwa ukuthi izinto zokusetshenziswa ezisetshenziselwa kuyo zihlanzekile kakhulu. Kunesinye inzuzo: I-Panangin itholakala ngesimo se-dragée esinemibala yokuzivikela, kanti i-Asparcum isesimweni samathebulethi kuphela. Okokuqala kuyamukeleka ezigulini eziphethwe izifo ezivuvukalayo zomzimba.
Qaphela
Isidakamizwa esichazwe sinamandla, ngakho-ke izinkomba nokuphikisana kwePanangin, okukufanele kuwe, kufanele kuboniswe udokotela kuphela. Isidakamizwa singanikeza imiphumela eminingi emibi:
- ukuxuba, i-paresthesia;
- ubomvu besikhumba sobuso;
- ukunciphisa kwengcindezi;
- ukuhlanza, isicanuca kanye nesifo sohudo;
- evutha emgodini wesisu (nge- gastritis ene-asidi ephezulu);
- umuzwa wokushisa;
- ukucindezeleka kokuphefumula.
Kuyingozi ukuthatha i-Panangin ngokubambisana ne-beta adrenoblockers, i-potassium-sparing diuretics, i-heparin, i-cyclosporine, i-ACE inhibitors.