Umkhuba we-bilirubin egazini labesifazane

I-Hemoglobin ne-erythrocytes, ezenzile imisebenzi yazo, zingaphansi kokusebenza esibindi. Ngenxa yezinqubo ezinjalo, i-bilirubin yenziwa - i-pigment eluhlaza okwesibhakabhaka. Kuyinto inkomba yesibindi nesiphele, izindlela zokusebenzisa umzimba. Ngakho-ke, isimiso esamukeleka kakhulu se-bilirubin egazini labesifazane kubhekwa njengenye yamaphuzu aphambili ekwenzeni izivivinyo ze-laboratory ukuze kutholakale izifo ezihlukahlukene ze-hepatological, endocrine kanye nokugaya.

Isimiso se-bilirubin esiphelele ekuhlaziyweni kwegazi kwabesifazane

Ukwakhiwa kwe-bilirubin kuqala ngamaseli abomvu egazi aqukethe i-hemoglobin futhi athuthe umoya-mpilo kuzo zonke izicubu ezithambile nezitho zangaphakathi. I-Erythrocytes, isikhathi esiphelelwe yisikhathi, faka u-spleen nomnkantsha wamathambo, kanye nesibindi, lapho izinqubo zokubhujiswa kwazo zenzeka khona. Ngenxa yokuhlukaniswa kwala maseli kanye nenxenye ye-hemoglobin, i-bilirubin ikhishwa. Okokuqala, akuqondile futhi kuyingozi emzimbeni, ngakho-ke ku-parenchyma yesibindi ibuyisela ama-enzyme akhethekile okuguqula leli qembu libe yi-bilirubin eqondile. Impahla eboshiwe ixiliswe nge-bile, ngemva kwalokho ingena emathunjini futhi ihlushwa ngokwemvelo kanye nendwangu.

I-Bilirubin kuleli cala iqukethe i-urobilin ne-stercobilin, lezi zibazi, ezinika umthunzi womugqa nomcengezi, ngokulandelana. Ngakho-ke, lapho ukuhlushwa kwe-compound okucatshangelwayo kwanda, umbala wokukhulelwa nakho uyashintsha. I-urine ithola umbala omnyama, futhi indwangu iphenduka mhlophe.

Umkhuba we-bilirubin esiphelele noma ophelele egazini labesifazane uvela ku-3.4 kuya ku-17.2 μmol / l. Uma kukhona umlando wesifo sesibindi, umlando wakamuva we-hepatitis yegciwane, ama-indices angaba kusuka ku-8.5 kuya ku-20,5 μmol / L, alandelwe ukujwayelekile.

Kumele uqaphele ukuthi inani elicacisiwe libhekwa njengelungile uma yonke imithetho iboniswa uma kudluliswa ukuhlaziywa:

1. Ungadli ngehora lesifundo. Kungcono ukuyeka ukudla amahora angu-12, kodwa ake sithi isikhawu samahora angu-4.
2. Ungadli ikhofi kanye nanoma yiziphi iziphuzo eziqukethe i-caffeine ngaphambi kokunikela ngegazi.
3. Ungaphuzi i- hepatoprotectors , ama-choleretic amalungiselelo, imithi ehlanza igazi (i-aspirin, i-heparin, i-warfarin).
4. Ungadlali, ungadli ngaphambi kokucwaninga.

Isikhathi esihle kakhulu sokulethwa kwegazi elibizayo cishe ngehora lesishiyagalolunye ekuseni.

Iyini isimiso se-bilirubin eqondile egazini legazi emantwini?

I-pigment yellow-green-pigment noma i-bilirubin i-glucuronic acid, ekulungele ukudonswa emzimbeni, akumele idlule i-4.3 μmol / l (kwabanye besifazane - kufika ku-7.9 μmol / l enezibindi ezikhona kanye nezifo ze-gallbladder) noma 20 -25% we-bilirubin yenani eliphelele.

Ukulinganisa okuncane okwesibhakabhaka oluhlaza okwesibhakabhaka egazini kuchazwa ukuthi iqiniso, njengoba umthetho, likhishwa ngokushesha emzimbeni ngokusebenzisa i-rectum kunye ne-feces ne-bile.

Iyini isimiso se-bilirubin engacacile egazini labesifazane?

I-compound echazweyo efomini elingavumelekile (ingqikithi engacacile), njengoba sekushiwo kakade, ingumuthi wezinto eziphilayo futhi ingaphansi kokucubungula okusheshayo kumaseli wesibindi. Ukugxila kwakhe yilokho okufundisayo kakhulu uma kunesidingo ukuhlola isimo se-hepatological system kanye nezinqubo zokuxuba.

Umkhuba we-bilirubin ongacacile noma wamahhala egazini labesifazane akufanele udlule i-15.4 μmol / l. Ngakho-ke, i-pigment engavaliwe ingaba ngu-70-75% we-bilirubin ephelele ye-plasma.

Kuyathakazelisa ukuthi ingxenyana engavamile, ebizwa nangokuthi ifomu yamahhala, ayiyona into eyodwa, kodwa isakhiwo esiyinkimbinkimbi sesikhashana ne-albumin. Ukunquma ukuhlushwa okuqondile kule laboratory kungenzeka kuphela emva kokubhujiswa kwaleyo molekyu futhi ushintsho lwayo lube yisimo somswakama emanzini.