I-Estradiol iyinhlangano yama-sex hormone evela eqenjini le-estrogen, elikhiqizwa ngokuyinhloko ngama-ovari (ngenani elincane lihlanganiswa ngama-gland adrenal). I-hormone level ye-estradiol kwabesifazane iyahlukahluka kuye ngesigaba sokujikeleza kokuya esikhathini. Ukukhiqizwa kwe-estradiol kukhuthazwa yi-hormone yokukhulula i-pituitary gland. Esihlokweni sethu, sifunda ukuthi yini echaphazela ihomoni yesifazane i-estradiol futhi yiyiphi ingozi uma kwenzeka ukwehlukana nokujwayelekile kwayo.
I-hormone estradiol - iyini inesibopho?
Njengoba sekushiwo kakade, ukukhiqizwa kwe-luteinizing (LH) kanye ne-follicle ekhuthaza (ama-hormone) ama-hormone emgodini we-pituitary uvuselela ukukhiqizwa kwe-estradiol ngama-ovari. Umsebenzi oyinhloko we-estradiol yi-potentiation yokukhula kwe-follicle kanye nokukhula kwesigaba sokusebenza se-endometrium. Ngesikhathi sokuvuthwa kwe-ovulation, ubukhulu bezingqimba zangaphakathi ze-endometrium kumele okungenani kube ngu-10 mm. Ukuntuleka kwe-estradiol kuvimbela ukukhula nokuvuthwa kwe-follicle ephezulu - ngakho-ke, ukuvuthwa kungase kwenzeke. Ukukhula kwe-endometrium esebenzayo nakho kuzovinjelwa. Ezimweni ezinjalo, ngisho neqanda elivuthiwe ngokuphumelelayo alinakufakwa emdongeni wesibeletho futhi kuyoba nokukhulelwa kwesisu ekuqaleni.
Ekhuluma ngemisebenzi ye-estradiol, asikwazi ukwehluleka ukusho ukuthi nguye owenza owesifazane omuhle. Ngaphansi kwethonya le-hormone yesifazane i-estradiol, isakhi sabantu besifazane sakhiwa (isifuba esikhulu, isikhumba esincane esinobuhle obushelelayo kuze kube sezinkalweni), isikhumba siba bushelelezi futhi silky, futhi kuvimbela ukukhula kwezinwele ezindaweni ezivamile zamadoda (ubuso, isifuba, imilenze, isisu).
Ukuhlaziywa kwe-estradiol kwabesifazane
Ukuhlaziywa kwe-estradiol kwenziwa nge-sampling blood sampula esiswini esingenalutho. Izinga lama-estradiol hormone ngokuvamile lihluka kuye ngokuthi isigaba somjikelezo. Ngakho-ke, iqala ukuthuthukiswa kusukela ezinsukwini zokuqala zomjikelezo wokuya esikhathini (esigabeni se-follicular, izinga le-estradiol lisukela ku 57-227 pg / ml). Phakathi nomjikelezo, inani le-estradiol liyisilinganiso esiphezulu (ngaphambi kokuvuthwa izinga le-estradiol liphakathi kuka-27-476 pg / ml), okuyinto emahoreni angu-24 kuya ku-37 okuyokhipha ukubola kwe-follicle nokuqala kwe-ovulation. Ngemuva kwe-ovulation, izinga le-estradiol liyancipha kakhulu. Ngakho esigabeni sokuqeqesha kungu-77-227 pg / ml. Amazinga aphezulu e-estradiol kwabesifazane esigabeni sesithathu sokujikeleza kokuya esikhathini sibonisa ukuqala kokukhulelwa.
Ngesikhathi sokukhulelwa, izinga le-estradiol kubesifazane liyakhula kancane, lifinyelele inani eliphakeme ngaphambi kokubeletha. Emva kokulethwa ezinsukwini ezingu-4-5, izinga le-estradiol egazini liyehla kakhulu.
Izinga le-estradiol ngaphansi kwesimiso sabesifazane kungaba yizizathu ezilandelayo:
- ukubhema;
- ukudla kwemifino;
- ukulahlekelwa kwesisindo esibukhali;
- ukukhiqizwa kabi kwamahomoni ocansi;
- ukunqotshwa kwegundane le-pituitary;
- umsebenzi owenziwe ngokweqile.
- ukwandisa amazinga e-prolactin.
Ngesikhathi sokuya esikhathini, izinga le-estradiol liyancipha futhi lilinganiselwa ku-19.7-82 pg / ml. Ukwandisa izinga le-hormone ngesikhathi sokuya esikhathini sokuya esikhathini kungakhuluma ngezicubu ezimbi zama-ovari.
Izinga le-estradiol emadodeni
Emzimbeni wesilisa, i-estradiol ikhiqizwa ngezicubu zamathambo kanye nama-gland adrenal ngenani elincane. Ngokuvamile izinga laleli
Ngakho-ke, sihlolisise amazinga avamile e-estradiol kumuntu wesifazane, kanye nezizathu zokwanda nokuncipha. Ngokuntuleka kwe-estradiol emzimbeni wesifazane obangelwa ukuphuma esikhathini sokuqala, ukuhlinzeka nge-radiation ne-radiation, i-hypo- ne-amenorrhea, ukwamukelwa kwe-analogue yayo yokwenziwa kuboniswa. Ngakho-ke, ukulungiswa kwe-17-beta estradiol (estradiol e2) kufana ne-estradiol yemvelo futhi kuyatholakala njengamafutha ashubile, isisombululo samafutha, isipulisi se-nasal kanye namaphilisi. Isidakamizwa singathathwa kuphela emva kokubonisana nodokotela.