Lesi sifo sibizwa ngokuthi yi-nemorrhagic pneumonia nephritis, i-pulmonary hemorrhage noma idiopathic hemosiderosis. Igama layo langempela yi-syndrome ye-Goodpasture's. Lesi yisifo esingavamile kakhulu esithinta umuntu oyedwa ngesigidi. Noma kunjalo udinga ukwazi ngezici zalo, izimpawu nezindlela zokwelapha.
Izimbangela eziyinhloko nezimpawu ze-Goodpasture Syndrome
Lesi yisifo esiyinkimbinkimbi se-autoimmune esihlotshaniswa neziphazamiso nezilonda zezingxenyeni ezisisekelo ze-lung alveoli. Ngokucacile, i-syndrome iqala kubantu abane-immunity ebuthakathaka futhi ibhekene nokuqeda kwamaphaphu. I-syndrome yokunakekelwa okutholakala ngokungajwayelekile futhi iningi labantu abagulayo - abantu abasha. Lesi sifo sithanda amadoda phakathi kweminyaka engu-18 no-35.
Ukusebenza kwezesayensi nezindlela ezenziwe nge-Goodpasture's syndrome kubhalwe phansi kakhulu, kodwa akekho ososayensi okwamanje okwazi ukukhomba imbangela yalesi sifo. Kuyaziwa ukuthi i-syndrome isekelwe ekubunjweni kwama-antibodies othize, okusho ukuthi, kuthinta izinqubo zamakhemikhali eziyinkimbinkimbi emzimbeni. Konke lokhu njengomphumela kubangela umonakalo odongeni lwamasongo.
Kukhona iziphakamiso ukuthi isifo sika-Goodpasture singabangelwa ukutheleleka kwamagciwane noma ama-bacterium (njengokuthi, isibonelo segciwane lesandulela ngculaza). Ngaphezu kwalokho, izici ezingaphandle zingathinta nomzimba omzimba. Njengoba umkhuba ubonisile, ababhemayo kusuka ekuguleni kwamaphaza bahlushwa kaningi. Izingozi nabantu abasebenza emagcekeni anemvelo yamakhemikhali, kanye nalabo abaphuza imithi ethile, bavezwa.
Ukuphikisana mayelana nezimbangela zesifo, akumele sikhohlwe mayelana nesimo sezakhi zofuzo, nakuba esimweni se-Goodpasture's syndrome le nguqulo ingase ibe iphutha. Futhi abanye ochwepheshe futhi bakholelwa ukuthi lesi sifo sibhekene nesimo se-hypothermia evamile.
Izimpawu zokuqala ze-Goodpasture's syndrome zifana kakhulu nokubonakaliswa kwe-pathologies yendabuko ye-pulmonary. Isici esiyinhloko esihlukanisayo siyithuthuka ngokushesha. Ngokungafani nokubandayo okuvamile, isifo sohlelo lokuhlelwa kwesisu kusukela ekuqaleni kuze kube sesiteji esinganakwa kakhulu singaqhubeka ezinsukwini zezinsuku.
Ukubonakaliswa okuyinhloko kwesifo kuhlanganisa:
- i-hemoptysis (ngezinye izikhathi imifudlana yegazi ibonakala ku-sputum, ngezinye izikhathi ama-clots amancane egazi aphikisiwe);
- ubuthakathaka;
- ukulahlekelwa kwamandla omthetho;
- ukuphefumula ;
- ukuzwa okungathandeki esifubeni;
- ukwehla okubukhali kwesisindo somzimba;
- ukwanda kokushisa;
- ukuthuthukiswa kokuhluleka kwenqunu;
- ukwehla kwe-hemoglobin.
Ukuxilongwa nokwelashwa kwesifo sokuphumula
Uma ungayinaki isifo sika-Goodpasture, leso sifo singase siholele ekufeni. Ukuze ugweme ukwelashwa okwesikhashana futhi okunzima kakhulu, ngezinsolo zokuqala kuyadingeka ukubonisana nochwepheshe. Thola
Egazini legulane, isifundo sizokwazi ukunquma ukuthi kukhona ama-antibodies aqondile. Ngaphezu kwalokho, ukusola kungabangela ukunciphisa i-hemoglobin namazinga aphezulu amangqamuzana egazi obomvu. Esivivinyweni segazi jikelele se-Goodpasture's syndrome sibonisa inani elikhulu lamaprotheni. Ezindaweni ze-roentgenogram izindawo zokuvuvukala zibonakala ngokucacile.
Ukwelashwa kwesifo sokuphutha komzimba ngisho naseziqaleni zokuqala kufanele kube nzima. Ngokuvamile inkambo yokwelapha ihlanganisa izidakamizwa ze-hormonal kanye nesistiostatics. Ezinye iziguli kudingeka zibonise ukwelashwa esikhundleni - ukumpontshelwa kwe-plasma nobukhulu be-erythrocyte. Uma lesi sifo senza umsebenzi wezinso wehlile, i-dialysis, futhi ngezinye izikhathi ngisho nokufakelwa, kungadingeka.