I-progesterone iyi-hormone ye-steroid ekhishwa ngumzimba wesilisa nowesilisa, ikakhulukazi amacilisi nama-ovari ngokubandakanyeka okungekho emthethweni kwe-cortex e-adrenal. I-progesterone ithathwa njenge-hormone yokukhulelwa: ikhiqizwa umzimba ophuzi izinsuku ezingu-12 kuya kwezingu-14 ngaphambi kokuqala kokuya esikhathini, futhi lapho kuqala ukukhulelwa izinga lakhe liqhubeka liphakeme kuze kube sevikini le-16 lokukhulelwa, lapho umsebenzi wokukhiqizwa kwe-hormone kanye nokudla komfutho kuphethwe yi-placenta.
Nini ukuhlola i-progesterone?
Isikhathi esiphezulu kakhulu sokuthatha izivivinyo ezingeni le-progesterone kwabesifazane abakhulelwe yinkathi kufika ezinyangeni ezingu-4 zokukhulelwa. Ngokuvamile ukuhlaziywa kunikezwa ngesikhathi sokubhalisa, futhi ngezikhathi ezithile emva kwalo.
Kwabesifazane ngaphandle kombuzo, lapho banikela ngegazi ku-progesterone, kufanele kuvunyelwane nodokotela oya khona. Phela, ngomjikelezo wosuku lwezinsuku ezingu-28, igazi le-progesterone kufanele linikezwe ngosuku lwe-22 lomjikelezo, okungukuthi, emva kokuvuthwa, lapho izinga layo likhuphuka. Ngomjikelezo omude, isibonelo, kuze kube yizinsuku ezingama-35, i-progesterone inikezwa ngosuku lwama-25-29 womjikelezo. Ukulethwa kokuhlolwa kwaleli hormone kunoma yikuphi okufanele kuwele esigabeni sesibili somjikelezo.
Ungathatha kanjani i-progesterone ngendlela efanele?
Noma yikuphi ukuhlaziywa, ngaphandle kwezimo zesikhashana, kunemibandela ethile yokuletha. Ukuhlaziywa kwe-progesterone kwenziwa ngesisu esingenalutho, ngemuva kokuba isidlo sokugcina sidlule amahora angu-6 kuya kwangu-8. Kunconywa ukuthatha ukuhlaziywa ekuseni, kodwa uma ubona isikhathi samahora angu-6 phakathi kokudla, singathunyelwa emva kokudla.
Nini ukuthatha i-pro-proton-17-OH?
17- I-progesterone ayiyona i-hormone, kodwa isandulela, ngakho kuthathwa izinsuku ezingu-4 kuya kwezingu-5 zomjikelezo. Ngesikhathi sokukhulelwa, ukuhlaziywa kwe-17-OH progesterone akuyona imininingwane kakhulu, njengoba kubaluleke nakakhulu imvelaphi yayo ngaphambi kokukhulelwa kanye nengane esanda kuzalwa.
Amanani we-progesterone
Ukuhlushwa kwama-hormone ngokuqondile kuxhomeke esigabeni somjikelezo, ukuhlushwa okuphezulu kakhulu esigabeni sokuqapha.
I-progesterone:
- isigaba se-follicular - 0,32 - 2,23 nmol / l;
- isigaba se-ovulatory - 0.48 - 9.41 nmol / l;
- Isigaba sokulinda - 6.99 - 56.63 nmol / l.
Ekukhulelwe, amazinga e-progesterone anjengoba:
- I trimester - 8,9 - 468,4 nmol / l;
- I-II trimester - 71.5 - 303.1 i-nmol / l;
- I-III trimester - 88.7 - 771.5 i-nmol / l.
Isilinganiso se-progesterone emadodeni ngu-0.32-0.64 nmol / l.
Ukuhlaziywa kwe-progesterone kufanele kunikelwe ekulungiseleleni ukukhulelwa, ngezinkinga ezidalwa yi-adrenocortical (isifo sika-Addison), futhi kunezimo ezithile ezihambisana nokwanda kwezinga le-progesterone:
- ukukhulelwa;
- ukuhluleka kwezinso;
- i-amenorrhea;
- ama-cysts omzimba ophuzi ;
- izilonda ze-placenta;
- uterine igazi.
- Izinga eliphansi le progesterone liboniswa yizimo ezilandelayo:
- ukukhulelwa ngaphambi kwesikhathi;
- usongo lokukhulelwa kwesisu;
- ukuphuma kwegazi;
- ukuvuvukala okungapheli kwesitho sangasese;
- ukubambezeleka kokuthuthukiswa komntwana;
- ukuthatha imithi ethile.
Uma uthatha noma yimiphi imithi ngenkathi uthatha uhlolo lwe-progesterone
Izinga eliphakeme le-progesterone kwabesifazane cishe libonisa ukukhulelwa, kanti emadodeni kuwuphawu lwezinqubo ze-neoplastic zezinhlayiya ze-adrenal noma ama-testicles.
Ukulungiswa kokuphulwa kwezinga le-progesterone esetshenziswa njalo ngezijovo ze-progesterone 1%, i-2% noma i-2.5% - izixazululo zama-hormone amafutha, ngokuvamile e-almond noma amafutha omnqumo, noma amafomu we-tablet e-progesterone, okuvumela isikhathi esifushane kunokwenzeka ukuthi ulungise isizinda se-hormonal.