I-hormone-evuselela i-hormone (i-FSH) i-hormone ekhishwa uhlelo lwe-hypothalamic-pituitary, ngokuqondile - ku-pituitary. Umthethonqubo wokukhiqiza kwawo wenziwa yi-hypothalamus, futhi ukuhlushwa kwe-FSH ngokuqondile kuncike ekutheni izinga lama-hormone ocansi egazini.
Ngokunciphisa kancane ekugxilweni kwabo, ukugqugquzelwa kwesakhiwo se-FSH kwenzeka, futhi ezingeni eliphakeme - ukuqala kwe-horlicone-stimulating hormone kwehla. Futhi kunciphisa ukuhlanganiswa kwe-FSH inhibin-B, esezinqamuzaneni zama-ovari nasezikhungwini ze-seminiferous zamadoda.
Izici zokukhiqizwa kwe-hormone
Ukuhlanganiswa kwe-FSH akuyona into ehlala njalo, kodwa uhlamvu oluxoshayo. Ngakho-ke, lapho i-hormone e-follicle-stimulating eyakhiwe yodwa ihlukaniswe ibe yigazi labesifazane, ukuhlushwa kwayo kuphakama kakhulu futhi kudlula isimiso esidingekayo se-2, futhi ngisho nezikhathi ezingu-2.5. Khona-ke izinga liyancipha kancane kancane. Ukuhlushwa okuphezulu kakhulu kuphawulwa esiteji se-follicular sokujikeleza kokuya esikhathini.
Amazinga e-FSH ngezikhathi ezahlukene zobomi besifazane
Okuqukethwe kwe-horlicone-okuvuselela i-hormone egazini kwanoma yimuphi owesifazane awunayo inzuzo njalo futhi ngokuvamile kuvamise imingcele ye-1.7-135 IU / l.
Ngakho okuqukethwe kwaleli hormone egazini labesifazane kuxhomeke esigabeni esithile (isigaba) somjikelezo wokuya esikhathini. Esigabeni se- follicular , i-FSH ivame ukuba ngu-3.49-13 IU / L, ekunciphiseni i-1.69-7.7. I-hormone enkulu kakhulu ekufinyeleleni kwe-ovulation - 4.69-22 IU / l. Phakathi nokukhulelwa okwamanje, ukuhlushwa kwe-FSH kunciphisa kunalokho, futhi kufinyelela emakethe angu-0.01-0.3 IU / L.
Ngenkathi ye-postmenopausal, okuqukethwe kwe-FSH kwanda, okubangelwa ukuvimbela ukuhlanganiswa kwe-estradiol ne-progesterone. Kule nkathi, ukuhlushwa kwe-FSH kufinyelela ku-26-135 IU / l.
Okuqukethwe kwe-hormone-okuvuselela i-hormone kungaphansi kwesimiso, okuholela ekuthuthukiseni:
- i-Callman syndrome;
- ukungabi nokukhiqizwa kwe-hormone yi-pituitary gland;
- izicubu ze-ovaries, amacilisi.
Futhi, ukwandisa ukuhlushwa kwe-horlicone-okuvuselela i-hormone ngaphezu kwesijwayelekile, kungaholela ezifweni ezinjengokuthi:
- izifo ze-gonads;
- isisu se-pituitary;
- i-cyst ovarian;
- ukuthuthukiswa kwe-gonads;
- ukukhulelwa ngaphambi kwesikhathi.
Okushoyo
I-FSH, eyakhiwe emzimbeni wesifazane, ikhuthaza ukuvuthwa kwe-follicles futhi iqinisekisa ukulungiswa kwazo kwenqubo yokugcoba. Le hormone iqondisa ngokuqondile isigaba sokuqala somjikelezo wonke wokuya esikhathini, umjikelezo we-follicular. Ngaphansi kwethonya laso, i-follicle iyanda kakhulu usayizi futhi iqala ukukhiqiza i- estradiol . Ekupheleni kwesigaba se-follicular, ukuhlushwa kwe-FSH kwanda kakhulu. Khona-ke i-follicle bursts, futhi kusukela kuyo iqanda elivuthiwe lishiya i-peritoneal cavity, okungukuthi, inqubo ye-ovulation yenzeke.
Phakathi nesigaba sesibili somjikelezo, i-luteal, i-FSH ikhuthaza ukuxhumana ngokuqondile kwe-progesterone. Uma owesifazane efinyelela eminyakeni engu-45-50, ukuphuma esikhathini, kwenzeka lapho i-estradiol ne-progesterone engasetshenziselwa ama-ovari, okuholela ekukhuleni emzimbeni we-FSH.
I-FSH iqukethe kumadoda, kodwa ekugxilweni okuphansi kakhulu. Le hormone iqala inqubo ye-spermatogenesis kumadoda amasha. I-FSH efaka isandla ekuthuthukisweni okujwayelekile kwamathambo amancane omzimba kanye nokwandisa izinga le-testosterone ye-hormone.
Ukuhlushwa okuphezulu kwe-FSH kubonakala lapho abantwana bezalwa. Kwabafana kunciphisa isigamu sonyaka, futhi kumantombazane - kufinyelela esimeni noma isilinganiso seminyaka eyi-1-1,5. Ngesikhathi esilandelayo okuqukethwe kwayo kwanda kuphela uma ufinyelela eminyakeni yobudala, lapho i-FSH ilawula inqubo yokukhulelwa.