I-Cholestasis - Izimpawu

Emzimbeni onempilo, i-bile ifihla ngasese i-colon-12 yokudla kokugaya. Endabeni yokuphazamiseka ekubunjweni, ukuhlukaniswa nokuhlukaniswa kwamanzi kagesi, i-cholestasis iqala - izimpawu zalesi simo zixhomeke ekutheni amandla alo, kanye nesayithi lapho inqubo ye-pathological ivela khona.

Kune-syndrome ye-intrahepatic ne-extrahepatic sylrome. Uhlobo lokuqala luhlotshaniswa nokuwohloka kokubambisana kwe-bile nokungena kwayo kuma-capillaries e-bile. Ifomu le-extrahepatic lesi sifo libhekene nokungasebenzi komshini we-bile duct noma ushintsho ekusebenzeni kwabo.

Izimpawu ze-hepatic cholestasis syndrome

Imibukiso emikhulu emitholampilo yesimo:

1. I-Xanthomas ne-xanthelasms. Esikhathini sikhumba kubonakala sengathi kukhona okuncane noma okuphakanyisiwe, okuncane, okwenziwe kahle kwe-hue ephuzi. Zitholakala endaweni, njengombuso, emahlokweni, entanyeni, emuva nangesifuba. Ngezinye izikhathi i-xanthomas itholakala ngaphansi kwezigulane ezincelisayo, emaphethweni ezintende zezandla.
2. I-Steatorrhoea ne-Acholia indwangu. Ngenxa yokuphulwa kwe-bile, kanye nokwamukela emathunjini amancane amakhemikhali e-lipid, izixuku ze-fecal zihlukaniswa futhi zibe yi-oily.
3. Ukunyamala komchamo. I-bilirubin ngokweqile egazini iholela ekuqoqweni kwayo okuningi emcinini, ngenxa yalokho ithola umthunzi weti elimnyama noma ubhiya omnyama.

Esinye sezibonakaliso ezithile kwi-cholestasis ukukhwabanisa kwesikhumba, okubangelwa ukucasuka kokuphela kwezinzwa nge-bile acid. Njengomthetho, lesi sibonakaliso sandulela i-jaundice.

Lezi zimo ezilandelayo zingase zihambisane nezifo ezingapheliyo:

• i-arthritis ye-rheumatoid;
• Sjogren's syndrome;
• ukudla kanye nokwelashwa kwemithi;
• i-splenomegaly;
• i-osteodystrophy ye-hepatic;
• i-hemorrhagic syndrome;
• i-cholelithiasis ;
• i-polyneuropathy;
• i-cerebellar ataxia;
• ukuwohloka kwe-retina;
• i-hepatic-cell insufficiency.

Izimpawu ze-cholestasis ye-extrahepatic

Zombili lezi zinhlobo zaleso sifo ziyafana, ngakho-ke ukufaka ukuxilongwa okunembile kuphela eklasini akunakwenzeka. Ucwaningo olwengeziwe lwezinsimbi luyadingeka.

Izimpawu ezicacile ze-cholestasis ngaphandle kwesibindi zihlanganisa:

• i-colic njalo ye-biliary;
• izimpawu ze- cholangitis ;
• ukukhushulwa kwe-pancreatitis;
• okusheshayo noma okwenzeka ngesikhathi esisodwa kwe-pruritus nge-jaundice;
• ukungabi khona kwesibindi esandisiwe;
• ukuthuthuka okusheshayo kwe-pathology.