Ama-adrenoblock noma i-adrenolytics yizidakamizwa eziphuza noma ezivimbela ukuhamba kwemizwa, "bavala" ama-receptors asezindongeni zegazi nemithambo yegazi, esabela ku-adrenaline ne-norepinephrine. Uhlu lwamalungiselelo-adrenoblockers luba lukhulu njalo ngonyaka. Ake sizame ukuthola ukuthi yiziphi izinhlobo ze-adrenolytics ezikhona, futhi nokuthi yiziphi izifo ezisebenzayo.
Yiziphi izidakamizwa ze-alpha ne-beta-adrenoblockers?
Izinhlobo eziyinhloko ze-adrenoblockers yizi:
- i-alpha-blockers;
- beta-blockers.
Ngokuya ngohlobo lwe-adrenolytics luthinta ama-receptors enye yezinhlobonhlobo ezimbili.
Ama-adrenoblockers ahlukene anefomu lezindlela ezahlukene. Ngakho i-adrenolytics ikhishwa efomu:
- amaphilisi;
- i-ampoule nezixazululo zomjovo;
- amaconsi.
I-Alpha receptor blockers
I-Alpha-adrenoblockers emzimbeni yenza kanje:
- ukwandisa imifino encane, kuyilapho unciphisa umthwalo enhliziyweni;
- ukunciphisa ukucindezela komzimba, ukunciphisa ukumelana kwamakhemikhali wegazi kanye nomthwalo kumisipha yenhliziyo;
- ukuthuthukisa ukujikeleza kwegazi;
- ukunciphisa ingcindezi emjikelezweni omncane (wamaphayona) wokuhambisa;
- cholesterol ephansi;
- ukunciphisa ukuhlunga kwegazi ngegazi.
Iqembu lama-block-receptor blockers liqukethe izidakamizwa ezisetshenziswa kulezi zifo ezilandelayo:
- ukucindezeleka komzimba;
- i-migraine ;
- i-endarteritis;
- i-spasm yezitsha zokubuyisela.
I-Alfa-adrenoblockers isetshenziswa ngokuphumelelayo ekwelapheni okuyinkimbinkimbi ye-prostatitis emadodeni.
Ukungafani kokusetshenziswa kwe-alpha-blockers yizifo:
- i-hypotension ye-arterial;
- i-atherosclerosis;
- i-infarction ye-myocardial;
- uphawu lwe-renal noma lwe-hepatic insufficiency.
Uhla lwamalungiselelo athandwayo e-alpha-blockers:
- I-Dihydroergotoxin;
- I-Urapidil;
- I-Nicergoline;
- I-Fentolamine;
- I-Pyrroxane;
- ITropafen;
- I-Prazosin hydrochloride;
- Butyroxane.
Ukuze uthole ulwazi! Esikhathini esidlule, izidakamizwa ezivela kuhlu lwe-α-blocker zazisetshenziselwa ukwelashwa kwemithi yokwelashwa kwazo zonke iziguli ngaphandle kokungafani, kodwa ngenxa yocwaningo lwezokwelapha lwembula ukuthi kwezinye izimo isicelo sabo singaholela ekuhlaselweni kwenhliziyo.
Beta-receptor blockers
Ukuphathwa kwezidakamizwa ze-beta-blocker kuholela emthonjeni olandelayo:
- kunciphisa izinga lenhliziyo;
- kunciphisa ukucindezelwa kwegazi;
- ukuphikiswa kwamangqamuzana e-muscle yenhliziyo kuya ekwenzeni i-oksijini yindlala ku-ischemia;
- ithuthukisa ithoni yemithambo yegazi;
- ukubunjwa kwe-thrombocytes kuvinjelwe;
- ukwandisa ukugeleza kwe-oxygen zibe izicubu zomzimba;
- umsebenzi wezitho zangaphakathi kanye nezigcawu ze-secretory zizinzile.
Izinkomba zokusetshenziswa kwezidakamizwa ohlwini lwe-β-blockers ziyizifo ezifana nalezi:
- i-glaucoma;
- ukucindezeleka komzimba;
- angina pectoris;
- i-arrhythmia yenhliziyo;
- i-infarction ye-myocardial;
- ukuhluleka kwenhliziyo;
- i-thyrotoxicosis ;
- i-cardiomyopathy.
Phakathi kokuphikisana nokusetshenziswa kwezidakamizwa zalolu hlobo kukhona izinombolo zezifo, kuhlanganise:
- isifo sikashukela mellitus;
- i-asthma ye-bronchial;
- I-COPD (isifo se-chronic obstructive pulmonary);
- ukuqeda ukuqina kwe-atherosclerosis.
Kuhlu lwe-beta-blockers yesizukulwane esisha, izidakamizwa:
- I-Cordanum;
- I-Anaprilin (i-Propranolol);
- I-Metoprolol;
- I-Bisoprolol (Concor);
- I-Nebilet (Nebivolol);
- I-Betaxolol (Lokren);
- Aptin;
- I-Betazprin;
- I-Esmolol et al.
Kubalulekile! Nakuba ezinye izidakamizwa-i-adrenoblockers zingathengwa kuma-pharmacy ngaphandle komshwalense, kodwa kufanele zisetshenziswe ngokusho komuthi kadokotela, njengoba imiphumela emibi ingatholakala ngaphandle kokwelashwa okuphumelelayo.
Adrenoblockers ye-Hybrid
Kukhona iqembu elikhethekile lezidakamizwa ezizibonakalisa ngesikhathi esifanayo njenge-alpha-adrenolytics nemithi ye-beta-adrenolytic. Lezi zi-adrenoblockers, njenge:
- I-Labetol;
- I-Procodolol.