Izimbangela zokwanda kwe-prolactin kwabesifazane ziyizinguquko zomzimba emzimbeni noma ezimweni zomzimba.
Ukuphakama kwemvelo kweprolactin
Ake sihlole ngokuningiliziwe ukuthi kungani i-prolactin yabesifazane isuka, futhi yiziphi izinguquko ezingaxhunyiwe. Ukwanda komzimba kweprolactin kuyisici ngesikhathi sokulala. Kungakapheli ihora ngemva kokuvuka, izinga le-hormone liye kancane kancane emazingeni ajwayelekile. Ukuphakama okulinganayo ezingeni lika-hormone kungenzeka ngemuva kokudla okuqukethe inani elikhulu lamaprotheni, kanye nezimo ezicindezelayo. Kuyaziwa ukuthi ukulala ngokobulili kuyisisusa esinamandla sokuvimba nokuqedwa kweprolactin. Ngenxa yezizathu zokukhula komzimba wezinga le-prolactin kwabesifazane kubalulekile ukufaka ukukhulelwa kanye nesikhathi sokudla ngebele.
Ukwandiswa kwamazinga e-prolactin njengesifo sesifo
Amazinga we-prolactin ephakanyisiwe e-pathologically egazini ngokuvamile abangela ukungahleleki kokuya esikhathini futhi aholela ekungenakwenzeka kokukhulelwe. Ngesikhathi esifanayo kukhona ukukhishwa kokuya esikhathini esibi. Ngaphezu kwalokho, ukwehla kwesifiso socansi kuyisici.
Ngaphansi kwemiphumela yesikhathi eside ye-hyperprolactinemia, ama-cysts emgodleni we-mammary kanye nokuthuthukiswa kokukhathazeka kubonakala.
Njengoba ubona, izimpawu zalesi simo aziyona ingozi. Ngakho-ke, ngaphambi kokuba uqale ukwelashwa, kubalulekile ukuthola ukuthi kungani i-prolactin iphakanyisiwe kwabesifazane, ngoba kubalulekile ukuqeda imbangela yalesi simo.
Kusukela ezimweni zokugula, izifo ezilandelayo zingabangela izimbangela ze-prolactin ephezulu kwabesifazane:
- Izicubu ze-pituitary ne-hypothalamus, ezihambisana nokukhushulwa kwe-prolactin. Kungenzeka njenge-prolactinoma engasese, kanye nesisu esikhiqiza ngamanani ama-hormone amaningi.
- Ukunqotshwa kwe-hypothalamus yesifo sofuba, i-sarcoidosis, kanye ne-irradiation yesitho.
- Ukunciphisa ukwakheka kwamahomoni wegciwane.
- I-polycystic ovary , uma kukhona ukungasebenzi kahle kwe-hormone yesondo.
- Izifo zesibindi, ukwehluleka kwesibindi esingapheli. Ukuba khona kwe-hyperprolactinemia kulokhu kungenxa yokuphulwa komzimba we-hormone.
- Izifo ze-cortex e-adrenal, okuholela ekusungulweni kwe-androgens futhi, ngenxa yalokho, ukungalingani kwe-prolactin.
- Ukukhiqizwa kwe-hormone e-Ectopic. Ngokwesibonelo, nge-carcinoma ohlelweni lwe-broncho-pulmonary, amaseli ase-atypical akwazi ukukhiqiza ama-hormone.
- Ukudla kwezidakamizwa ezithile ezifana neuroleptics, tranquilizers, anti-depressants, i-estrogen-progestogen ehlangene nabanye.
- Kwezinye izimo, isifo sikashukela esikhombisa abesifazane sihambisana nokwanda kwezinga leprolactin.