I-Photodynamic therapy (i-PDT) yindlela yokwelashwa, esetshenziselwa ikakhulu ukuphatha izicubu ezimbi, kanye nezinye izifo ze-dermatological nezifo ezithathelwanayo. Njengamanje, usekhona esiteji sokutadisha emtholampilo, ukuthuthukiswa nokuthuthukiswa, kodwa esebenzisekayo futhi esebenzayo, kokubili phesheya futhi nathi.
Indlela ye-photodynamic therapy ku-oncology
I-PDT ekwelashweni komdlavuza kuyindlela engabizi, indlela enomusa futhi ephumelelayo, evumela ukuthi ukhiphe izinhlobo ezihlukahlukene zezicubu ezimbi - eyinhloko, ephindaphindiwe, ephathelene nemetastatic. Ngokufanayo, ukwelashwa kwe-photodynamic kuboniswa ukuthi:
- i-melanoma , umdlavuza wesikhumba;
- izicubu zomlomo zomdlavuza, umlomo womlomo, ama-auricles, izinkophelo;
- umdlavuza wamaphaphu, i-bronchi, i-trachea;
- izimo ezimbi zomlomo wesibeletho, i-vulva, isifuba, isisu, isisu, isambiso, njll.
Le ndlela isekelwe ekubhujisweni kwamangqamuzana e-tumor ngenxa yethonya lamafomu asebenzayo oksijeni, okwakhiwa ngesikhathi sokuphendula kwe-photochemical. Izingxenye ezidingekayo zale mpendulo zilula kwamanye ama-wavevel (red), i-oksijeni, ehlale ikhona ezicubu zomzimba, kanye nezinto ezikhethekile - izithombeensitizers.
Ama-photosensitizers yizinto ezibonakalayo ezikwazi ukubona nokudlulisa amandla okukhanya. Ama-photosensitizers akhethekile ajojelwa emzimbeni wesiguli (ngokulandelana, ngokufaka isicelo, ngomlomo), futhi aqoqele ngokuqoqa amangqamuzana omdlavuza, ngenkathi engeke alinde amangqamuzana anempilo.
Khona-ke, ngaphansi kwethonya lokukhanya, i-oksijini emathisheni omdlavuza iwela esimweni esisebenzayo esikhethekile, lapho siqala khona ukuphazamisa izakhi zangaphakathi zamangqamuzana omzimba. Njengomthombo wokukhanya, njengomthetho, ukufakwa kwelaser kusetshenziswa. Ngakho-ke, lesi sifo sibulawa. Le nqubo ithatha amasonto amabili kuya kwangu-3. Ukwelashwa kwe-Photodynamic kungahlanganiswa ne-radiotherapy noma i-chemotherapy, kanye nezindlela zokuhlinzwa, okuvumela ukufezekisa imiphumela ephawulekayo ekwelapheni umdlavuza.
Kukhona ukwelashwa kwe-photodynamic ku-oncology kanye nokunye ukuphikisana:
- isifo senhliziyo nesibindi;
- Izifo zenhliziyo (isisombululo sigaba);
- ukukhulelwa kanye nokulahlwa;
- ukucindezeleka kuya kwi-photosensitizer.
I-Photodynamic therapy ku-stomatology
Muva nje, i-PDT iba yinto evame kakhulu ekwelapheni izifo zamazinyo namazinyo, okungukuthi:
- i-periodontitis ;
- gingivitis;
- i-alveolitis;
- i-discolorite;
- caries.
Ngosizo lwe-photosensitizer futhi kusetshenziswe i-laser beam, ukuchithwa kwemithi okuphelele kuyenziwa, okuyinto ehlukile efanelekile kumithi elwa namagciwane lapho ukwelashwa izifo ezitholakala khona.
Ukwelashwa kwe-Photodynamic ku-cosmetology
Indlela yokwelashwa kwe-photodynamic isetshenziselwa kakhulu ukwelashwa kwamacne, nakwezinye izindawo ze-cosmetology ne-dermatology - ukuqeda izimpawu ze-couperose, i-rosacea, i-hyperpigmentation, i-photoaging, i-keratoma, i-psoriasis, i-vitiligo, i-mycoses.
Ama-paintensens-photosensitizers asetshenziswe esikhumbeni ezindaweni eziyinkimbinkimbi zibuthelela kumaseli angalungile namadala (njengama-zone angenawo amandla kakhulu). Ngenxa yokuphendula kwe-photochemical ngaphansi kwesenzo se-laser, ukufa kwamaseli awonakele kwenzeka. Kanye nalokhu, inqubo iholela ekugqugquzelweni kokuhlukaniswa kwama-stem cells we-basal ungqimba wesikhumba ukuthatha indawo yamaseli abhujisiwe, nokuvuselela kokukhiqizwa kwe-collagen.
I-Photodynamic therapy ku-ophthalmology
I-Photodynamic therapy iyindlela ehlukile yokuhlinza laser lapho ukwelashwa izifo ezithile zeso. Ngokuyinhloko, ngokunciphisa ukukhula kwemithambo yegazi, le ndlela iyakwazi ukuvimbela ukuqhutshwa kohlobo olumanzi lokuguquka kwe-retinal.
Ukwelashwa kwe-Photodynamic - imiphumela emibi
Umphumela owodwa ohlangothini wendlela yukuzwela okwedlulele okwesikhashana ekukhanyeni. Mayelana nalokhu, iziguli emva kwenqubo ye-PDT kufanele isikhathi esithile sokugwema ukukhanya kwelanga.