I-leukemia, evela ngokushintshwa kwamaseli ejwayelekile egazi ngamaproseshi e-leukocyte angavuthiwe, ibizwa ngokuthi i-leukemia ephawulekayo ye-myeloblastic. Nakuba lesi sifo singavamile, lesi sifo siqhubeka ngokushesha futhi kunzima ukuphatha. Ingozi yokulimala ikhula ngokukhula.
I-leukemia ye-myeloblastic eyingozi - izimbangela
Misa ngokucacile izici ezithinta ukuguqulwa kwamaseli emnothweni wamathambo, okwamanje akunakwenzeka. Izimbangela ezingenzeka zokuhlukumeza zihlanganisa:
- ukungcola kwemvelo;
- i-irradiation ne-radiation;
- ukutholakala kwamakhemikhali afana ne-benzene kanye ne-formalin;
- i-pathologies yokuzalwa yesifo (i-Down's disease, i-Wesler-Fanconi anemia, i-Bloom's syndrome);
- isikhathi eside kakhulu emzimbeni wemithi ye-cytotoxic.
Ukuhlukaniswa kwe-leukemia ephawulekayo ye-myeloblastic
Ngokwesimiso sezokwelapha ngokuvamile esamukelwe, lesi sifo esicatshangelwayo sihlukaniswe ngama-subtypes alandelayo:
- I-M0 - i-leukemia engeyona i-lymphoblastic ehlukaniswa kancane;
- i-myeloblastic leukemia ye-M1 ngaphandle kwempawu zokuvuthwa;
- i-myeloblastic leukemia le-M2 enezimpawu zokuvuthwa;
- i-promyelocytic leukemia i-M3;
- i-myeloblastic noma i-myelomonocytic leukemia i-M4;
- i-myelomonocytic leukemia ene-combination of bone marrow eosonophilia M4 (eo);
- i-monoblast ejulile i-leukemia i-M5a;
- i-leocemia ye-monocytic ejulile M5b;
- I-erythrocyte i-leukemia ejulile i-M6a;
- i-erythroid egcwele i-leukemia i-M6b;
- i-leukemia ye-megakaryoblastic ye-M7;
- i-leopemia ye-basophilic i-M8.
I-myeloblastic leukemia ephawulekayo - izimpawu
Ekuqaleni kokuguqulwa kwamaseli, lesi sifo asibonakali. Ngemva kokuqoqwa ngokweqile emathinini emasaka, amafomu e-leukocyte angapheli aqhutshwa yigazi emzimbeni wonke futhi ahlale e-spleen, i-lymph node, isibindi nezinye izitho.
Isigaba sokuqala sesifo sibonakala ngezibonakaliso ezinjalo:
- ukwehla emisebenzini yokuzivikela yokuzivikela, ngenxa yalokho isiguli sithandwa yizifo eziningi;
- ubuthakathaka;
- ukwanda kancane ekushiseni komzimba.
Njengoba esikhundleni samangqamuzana anempilo ezitho zangaphakathi kanye nezibungu zamangcwaba nama-clones ashintshwe ukuguqulwa, izimpawu ezilandelayo ziphawulwe:
- i-meningitis ;
- i-pneumonia;
- ukuphuma kwepulmonary kanye nesisu;
- izinkinga ezinkulu zezifo ezithathelwanayo.
Esigabeni sesibili, ngaphandle kokunakekelwa okwelashwa okwanele, umuntu ufe ngenxa yezinhlungu zangaphakathi.
Ngokuvamile, izigaba ezingenhla zokuthuthukiswa komdlavuza zihlukile, ngakho-ke ukuchazwa kokuxilongwa kwe-acute myeloblastic leukemia cishe kunomthelela omuhle ngezokwelapha ngesikhathi esifanele. I-pathogenesis ye-Wavy yalesi sifo yenza kube lula ukuyiqonda ekuqaleni kwezinyathelo ngokusebenzisa ukuhlola kwe-laboratory yegazi nokuhlushwa kwezici ezikulo.
Ukwelashwa kwe-leukemia e-acute myeloblastic
Njengezinye izinhlobo ze-khansa, i-leukemia idinga i- chemotherapy enezigaba ezimbili eziyinhloko:
- ukuqedwa kwamangqamuzana athola ukuguqulwa kwezakhi zofuzo;
- ukwehla kwenani lama-clones ezinhlakeni zomzimba.
Ukwelashwa kuqhutshwa izifundo eziningana ezinezikhathi ezincane kanye nokwamukelwa kwemithi ngesikhathi esisodwa okwehlisa ukuvuvukala. Ngaphezu kwalokho, ukuphakanyiswa kwamavithamini, ama-immunomodulators. Okubi
Enye yezindlela eziphumelela kakhulu zokwelapha lolu hlobo lomdlavuza wegazi yi-transplantation yamathambo. Le ndlela ihilela ukuguqulwa ngokuphelele kwezicubu ezingasebenzi ngendlela enempilo. Ukwelashwa kubonisa ukuthi ngaphezu kwengxenye yeziguli kuleli cala baphulukiswa ngokuphelele.