I-jaundice yisimiso lapho isikhumba, isikhala nesibungu semvukuzane zitholakalayo. Ivela ngenxa yokuqoqwa ngokweqile kwe-bilirubin egazini, kanye nokufakwa kwayo ezinhlobonhlobo. Kunezinhlobo eziningana ze-jaundice kuye ngokuthi i-pathogenesis yayo. Kungaba yi-hepatic, adrenal and adrenal.
I-jaundice ye-Hepatic
Ukubonakala kwe-jaundice ye-hepatic kubangelwa ukuphulwa kwe-intrahepatic bilirubin metabolism. Esimweni esinjalo, umbala ogqamile kakhulu we-sclera, isikhumba neserawu yisici. Kunezinhlobo ze-jaundice ezikhula esibindi:
- I-enzymopathic - uphawu lokungasebenzi okwanele kwama-enzyme, okuyizona ezithinta izinqubo ze-bilirubin).
- I-cholestatic - lolu hlobo lwe-jaundice lwenzeka ngesifo sofuba esingapheli, noma yikuphi ukulimala kwesibindi esinobuthi, i-cholestasis enobungozi ephindaphindiwe, i-cirrhosis eyinhloko ye- biliary kanye ne-hepatosis yabesifazane abakhulelwe).
- I-Hepatic-cell - ivela nge-hepatitis, cirrhosis yesibindi, ukuvezwa kwezidakamizwa, ukulimala kwesibindi kwesibindi nokusetshenziswa kwemithi ethile).
Ukuphazanyiswa kwegazi le-bilirubin ezinhlobonhlobo ze-jaundice ye-renal kungabangeli nje ukuphuziza kwesikhumba, kodwa futhi kunesihlungulu, izihlalo ezivame futhi ezixekethile, umkhuhlane kanye nobuhlungu ku-hypochondrium.
Hemolytic jaundice
I-jaundice ye-Hemolytic ibangelwa ukuhlakazeka okwedlulele kwamangqamuzana egazi abomvu kanye nezinga eliphakeme lokubunjwa kwe-bilirubin, okuyinto isibindi asikwazi ukukhipha ngokuphelele. Isimo esinjalo singaba sesibhedlela noma sitholakale. Ithengwa nge:
- i-anemia;
- i-hemoglobinopathy;
- i-infarction yamaphaphu ;
- i-lymphosarcoma.
I-jaundice yama-mechanical
Lolu hlobo lwe-jaundice, olunjenge-mechanical, luqala ngenxa yokugodla kwamadaysi e-extrahepatic bile. Lokhu kuvimbela ukugeleza okuvamile kwebhala ku-duodenum. Lesi simo, njengomthetho, siwumphumela wokuba khona kwamadayipi enqwaba yamatshe, i-tumor noma ama-parasites.