Isifo se-Paget singokwama-pathologies engokwemvelo. Ngokuyinhloko lesi sifo sithinta isifuba . Cabanga ngokuphulwa ngokuningiliziwe, ukugqamisa izimbangela zayo, izigaba, izimpawu nezindlela zokuzimisela, izindlela zokwelashwa.
Isifo sikaPaget - siyini?
Isifo se-Paget sesifuba sabizwa ngokuthi udokotela owahlola lesi sifo. Masinyane waqala ukuhlobana phakathi kwezinguquko ezitholakala kule nkinga, ngomdlavuza wesifuba. Ezimweni eziningi, ukwephulwa kwalolu hlobo kubhalwe ngesikhathi sokushintsha kwe-hormonal - ukuyeka esikhathini sokuqala, ukuyeka esikhathini sokuqala.
Umdlavuza wePaget, izimpawu zazo ezichazwe ngezansi, ukhula ngaphakathi kwebhande lesifuba, ngenxa yenkambiso yomdlavuza esifubeni. Izinguquko zanda esikhumbeni se-ingono. Kulesi simo, isifo esibuhlungu singase singathinti odokotela, isiguli ngokwayo. Ngezinye izikhathi, ukwephulwa kungabhalwa kwezinye izitho - umdlavuza we-extramammary. Kulesi simo, indawo yokugulisa, isisu, isinye isithintekile.
I-Paget's Cancer - Species
Umdlavuza kaPaget uyisifo sezinhlobonhlobo ezinemibono ehlukahlukene yemitholampilo. Ngenxa yalokhu, ngokuvamile akunakwenzeka ukuyihlolisisa ngezigaba zokuqala. Kuncike ekutheni i-pathology ebonakala kanjani, izici zenkambo yayo, lezi zinhlobo zezifo zilandelayo:
- Khipha ukukhishwa okukodwa. Ngalesi fomu esifundeni esiseduze, kuhlanganiswa izinsiza ezincane. Ngokuhamba kwesikhathi, baba izilonda.
- I-Examoid engapheli. Phezu kwe-ingono, ifomu le-crusts. Uma zisuswe, indawo encane yokwakhiwa kwe-intertrigo iyenzeka.
- Ifomu yengqondo. Kubonakala ukuba khona ebusweni bendwangu encane, i-pink hue, i-papules. Ngaphandle, zimbozwe nge-scaly, okuyinto ngokuhamba kwesikhathi idlula.
- Ifomu lokulonda. Phezu kwesifuba, ngalolu hlobo lwesifo, izilonda zenziwa, ngokucindezeleka phakathi. Ekubukeni kubonakala njengezintaba zomlilo.
- I-Tumor. Efaniswa nokubonakala kokubunjwa okunamandla, uhlobo lwesisu. It is localized ikakhulukazi esifundeni esondayo.
Ngokusho komtholampilo, ngamacala angu-50%, isifo sikaPaget sihambisana nezinguquko ezinkampanini ze-nipple-alveolar. Ku-40% weziguli ezine-palpation kanye nokuhlolwa, i-node ye-tumor ene-palp in endaweni ekhonjisiwe itholakala. Lesi sifo sitholwa kaningi ngokuhlolwa kokuvimbela, ngenxa yokuntuleka kwesithombe somtholampilo.
Umdlavuza wePaget - izigaba
Lesi sifo (umdlavuza) wePaget siqala kancane kancane, sinesiqalo esibuhlungu. Ngenxa yalokhu, abesifazane abaningi abaqapheli izinguquko isikhathi eside. Umdlavuza kaPaget, isigaba sokuqala sesi sifo, utholakala ukuthi ungavamile kakhulu, njengoba owesifazane engakhathazeki nganoma yini. Ngenkathi yokugula, kuvamile ukuhlukanisa izigaba ezine:
- isigaba 0 - i-tumor ivinjelwe ezicubu ze-epidermal, kuyilapho izinhlaka ezinkulu, ezijulile, ezimbi zingekho. Ama-protocols ahlale engashintshi;
- Isigaba 1 - kuhambisane nendaba yesifo somdlavuza webele, isilonda samadonsi omgogodla, lezi zinguquko zendawo eziseduze ne-ingono;
- isigaba 2 - sihlotshaniswa nomdlavuza webele we-intra-cellular;
- Isigaba sesi-3 - sibhekene nomdlavuza webele we-protrugal, umonakalo omkhulu wezicubu, i-foci eminingi.
Isifo se-Paget sezimpawu zesifuba
Umdlavuza we-Paget wesifuba, izimpawu zazo ezingekho ezinkathini zokuqala, ngokuvamile ziba isimanga kowesifazane ngokwakhe. Iziguli eziningi aziboni ushintsho esimweni sabo sempilo. Ukusola kungenziwa kuphela ngesisa esifubeni kanye nokuthola izimpawu. Ngaphezu kwalokho, endaweni yengono kukhona ukucasuka, ubomvu, ukukhishwa kwesikhumba. Uma umdlavuza wePaget uqala, ingono ingase ingabonakali - iwela ngaphakathi.
Ngenkinga yokugula njenge-Paget's disease, izimpawu zingase zinyamalale ngokuzumayo, kodwa lokhu akuwona ukubuyiswa. Ukunyamalala okwesikhashana kwezimpawu kuphawulwe ngokusuka ngemuva kwamafutha e-corticosteroid - abesifazane bathatha izimpawu ze-allergies. Ngokuqhubeka kwe-pathology, ukungena okuqhubekayo, isifo se-alveolar siqala. Ngenxa yalokho kuguqulwa, izimo nezilonda zakhiwa phezu kwesikhumba, bese kuthi i-crusts. Iziguli zirekhoda ukubukeka:
- itching;
- ukushisa;
- ingoma.
- ukuzwela okukhulu esifundeni sezinyosi.
Isifo se-Paget - ukuxilongwa
Ukuxilongwa "komdlavuza webele wePaget" kuvezwe ngesisekelo semiphumela yezifundo ze-laboratory, isithombe somtholampilo. Uma usola isifo, iziguli zinikezwa:
- ukuhlolwa kwe-cytological (ukukhipha ebusweni beglovu ethintekile)
- I-Histology - i-microcopy yesayithi lamathambo awonakele
- mammography.
Umdlavuza wePaget - ukwelashwa
Isifo se-Paget sesifuba sivame ukuphathwa ukwelashwa. Lona uhlobo oluyinhloko lokwelapha. Ngisho lapho kungekho izibonakaliso ezingenakulinganiswa, odokotela benza usizo olubanzi lokuhlinzeka. Ngesikhathi esifanayo, kubalulekile ukuhlola ama-lymph nodes axillary. Uma lesi sifo sihlangene nomdlavuza we-protocol ukungena ngaphakathi, i-mastectomy (ukususwa kwe-gland) yenziwa.
Ezinye izindlela zokwelapha lesi sifo zinomthelela ongaguquki. Ngenxa yalokhu, zisetshenziswe njengengeziwe. Phakathi kwabo kukhona:
- ukwelashwa kwemisebe ;
- i-chemotherapy;
- antiestrogen hormone therapy.
Umdlavuza webele we-Paget - ukubikezela
Ngesifo esifana nomdlavuza webele kaPaget, ukubikezelwa kwabesifazane akubi. Amathuba okuphindaphinda we-pathology, ukuqala kabusha kwesifo kuhlala ngemuva kokusebenza. Isibikezelo sincike ekuhlukumezeni kokukhula kwesisu. Isikhathi sokuphila esiphezulu se-Paget isifo seminyaka engu-3. Uma kukhona izingxenye ezingenayo ukungena, izibalo ze-metastase, le nkathi incishisiwe ibe yonyaka ongu-1.