Ama-hormone e-steroid yizinto ezenza umsebenzi wokuphila. Emzimbeni badlala indima ebalulekile. Amahomori anesibopho sokulawula izinqubo eziningi zomzimba ezibalulekile emzimbeni. Umzimba onempilo uveza lezi zinto ngokuzimela. Kodwa ngezinye izikhathi ngenxa yezinkinga zempilo ukugcina izinga lama-hormone e-steroid ngendlela evamile kuyadingeka ngosizo lwezidakamizwa zemithi.
Uhlu lwezidakamizwa nge-hormone ye-steroid
Leli qembu lezinto lihlanganisa i-corticosteroids nama-hormone ocansi. Emzimbeni, benza imisebenzi enjalo njengomthethonqubo we-metabolism nokukhula. I-hormone ye-steroid enesibopho sokuqinisekisa imisebenzi yokuzala yomzimba.
Izakhi ezikhungweni ze-cortex ezidalwa zikhiqizwa. Amakhomitha angatholakala emahlathini e-lipid ku-cytoplasm. Ngenxa ye-lipophilicity eyanda, izinto zingena kalula ngokusebenzisa izibilini zibe yigazi, futhi kusukela lapho zihambisa indlela eya emangqamuzaneni aqashelwa ngumzimba njengengozi.
Emzimbeni womuntu, ayikho indlela ekhethekile, lapho i-hormone ye-steroid iqoqa khona, ngakho-ke, ngemva kokubhujiswa kwezinto, ziqedwa emzimbeni. Konke okusele kuyi-precursor ye-hormone njengendlela ye-cholesterol ester kumaseli akhiqiza i-steroids. Futhi ngenxa ye-synthesis ye-hormone ye-steroid, ama-hormone peptide - izinto ezikhiqizwa yi-pituitary gland kanye ne-hypothalamus.
Emzimbeni womuntu ngamunye kunezinhlobo eziyisithupha eziyinhloko zamahomoni e-steroid:
- i-cortisol;
- i-estradiol;
- i-calcitriol (esikhathini esedlule - i-calcifolol);
- i-testosterone;
- i-progesterone;
- aldosterone.
Amaketanga ohlangothini amaningi alawo mzimba awancane - ahlanganisa kuphela ama-athomu e-carbon. Awekho ama-hormone ahlangene nhlobo. Futhi kuphela i-calcitriol isakhiwo esingaphansi noma esiyinkimbinkimbi.
Uma abesifazane bephazanyiswa ngama-hormone e-steroid, kunqunywe imithi ekhethekile. Imithi edumile kunazo zonke eyenza ama-hormone e-steroid emzimbeni yilezi:
- I-Hydrocortisone ;
- Dexamethasone;
- I-Cortisone;
- I-Estriol;
- I-Prednisone;
- I-Prednisolone.
Muva nje, amahomoni ase-steroid zokwenziwa asetshenziswe abesifazane ngokuphindaphindiwe kaningi. Izidakamizwa zisetshenziselwa ukuphatha izifo ezihlukahlukene futhi zigcine impilo enempilo yonke.
Ama-hormone e-steroid - imiphumela emibi
Imiphumela emibi kanye nokuphikisana okumele kusetshenziswe, mhlawumbe, ngisho nemithi eminingi engcolile. Kodwa uma kufika kuma-hormone, kudingeka uqaphele ngokukhethekile. Okokuqala, lezi zinto zingaholela kwezinye izinguquko ezingathandeki. Okwesibili, uma uhlukumeza ama-hormone, umzimba uzoyeka ukuzenzela wona, okuyinto emzimbeni kuyoba yinto engathandeki kakhulu.
Ukusetshenziswa okungalawulwa kwezidakamizwa nge-hormone ye-steroid kugcwele izinkinga ezilandelayo:
- ukubhujiswa kwesibindi;
- ukubonakala kwe- acne ;
- izifo zesimiso senhliziyo;
- ukuphulwa komsebenzi wezinso ezivamile;
- ukwanda kwengcindezi yegazi;
- ukwakheka kwezindwangu zegazi;
- ukwandisa amazinga e-blood cholesterol;
- ukuphazamiseka kwengqondo.
Ukuphikisana okuyinhloko kokuthatha ama-hormone e-steroid yilokhu:
- Akunconywa ukwamukela izimali zabantu abasha.
- Ama-hormone amahle angathinta impilo yabantu abanesifo senhliziyo, izinso nesibindi.
- Ukwenqaba ukuthatha imithi kufanele kube khona phambi kwezicubu ezinhle nezimbi.