Izidakamizwa zanamuhla ezingezona isifo sokuvuvukala zithatha enye yezindawo zokudumisa emithi. Unomphumela we-analgesic ne-antipyretic, ngokushesha ususe ukukhukhumezeka, uyeke ukuvuvukala nokunciphisa ubuhlungu be-syndromes. Ngenxa yalezi zakhiwo zisetshenziselwa kakhulu ukwelashwa kwezifo eziningi.
Izinkomba zokusetshenziswa kwezidakamizwa ezingezona ukuvuvukala
Ama-NSAID anamuhla atholakale ngendlela yokujola, ama-suppository, amaphilisi, ama-capsules, ama-gel namafutha. Ngokuvamile zisetshenziselwa izifo ezingapheli noma ezinzima, ezihambisana nobuhlungu obukhulu nokuvuvukala. Ngokuvame kakhulu kunqunyelwe ukuthi:
- i-osteoarthritis;
- i-gout;
- i-arthritis ye-rheumatoid;
- Isifo sikaReiter ;
- i-dysmenorrhea;
- i-migraines kanye nekhanda;
- ukuguqulwa kwamathambo;
- umkhuhlane;
- isifo se-postoperative syndrome;
- i-renal colic.
Amalungiselelo angenasidingo esakhiweni esisha
Amalungiselelo e-classic nonsteroidal acacile ngokusebenza nge-isoforms ye-cyclooxygenase: i-enzyme yokuvikela (COX-1) ne-enzyme yokuvuvukala (COX-2). I-enzyme yokuvikelwa yaxoshwa yibo, okwenyusa ukwehla kwemisebenzi yokuzivikela yezinambuzane ezimangcwabeni zesisu kanye nezifo ezihlukahlukene zomuthi wonke wamathumbu. Kodwa izidakamizwa ezingekho-steroidal ezilwa nokuvuvukala zalesi sizukulwane esisha zenza ngokuphambene - i-enzyme yokuvuvukala icindezelwe ngezinga elikhulu. Ngenxa yalokhu:
- ukuzivikela komzimba ekwenzeni ukwelashwa kunamandla;
- Imiphumela emibi ivela kancane kakhulu;
- isidakamizwa sisebenza ngokuphumelelayo.
Amalungiselelo angasetshenzisiwe esizukulwaneni esisha cishe ayithinti i-COX-1. Zonke zihlukaniswa izinga eliphezulu lokuphepha komzimba womuntu. Ezinye imiphumela emibi ngemuva kokusetshenziswa kwazo kusengenzeka. Kodwa lokhu kuboniswa kuphela uma ukungena kwezidakamizwa ezishaya izidakamizwa ezishaya izidakamizwa ezinde kakhulu. Kulesi simo, akufanele ikhanseliwe. Kwezinye izimo, udinga kuphela ukukhetha umthamo ongcono.
Imiphi imithi ehlobene nezidakamizwa zesimanje ezingekho steroid?
I-Oksikam - izidakamizwa zemithi engeyona i-steroidal. Leli qembu lezidakamizwa libhekene nokukhula kwengxenye yokuphila. Ngenxa yalokhu, isenzo sesidakamizwa emzimbeni sikhuliswa isikhathi eside, okuvumela ukunciphisa imvamisa yokuthatha imithi. I-Oksikamy ithathwe njengesizathu sokuthuthukiswa kwezidakamizwa zesimanje ezingenayo i-steroid.
Isibonelo sesizukulwane esisha se-NSAID ngu-Xefokam. Le mithi inekhono eliphakeme lokuhlaziya. Amandla akhe okusebenza angafaniswa noMorphine. Lokho kungumphumela ofana ne-opiate-ohlelweni lwesigungu sezinzwa futhi umlutha awubangeli.
Futhi izidakamizwa ezintsha ezingezange-steroidal eziphikisayo ziyi:
- I-Nimesulide - isetshenziselwa ukwelapha ubuhlungu be-arthritis kanye ne-vertebrogenic emuva. Ngemuva kokuphathwa kwayo, ukuvuvukala kuyanyamalala, i-hyperemia, izinga lokushisa lijwayelekile, futhi ukuhamba kuyathuthuka.
- I-Celecoxib imithi ehlisa isimo sesiguli nge-arthrosis ne-osteochondrosis. Ukuphumelela ngokulwa nokuvuvukala futhi
ususa ngokuphelele isifo sobuhlungu. - I-Meloksikam - isidakamizwa esinomphumela we-antipyretic, anti-inflammatory futhi ophawulwe kahle. Kungathathwa ngisho nesikhathi eside. Ikhiqizwa yi-Meloxicam ngendlela yamathebulethi, isisombululo sezijovo, amafutha okugcoba kanye nama-suppository.
Ukuhlukunyezwa okuphela kwezidakamizwa ezingenayo i-non-steroid ukuthi akuholeli ekutholeni okuphelele ku-osteochondrosis, i-arthrosis yamalunga nama- arthritis . Lapho ukwelashwa kwezi zifo, kuyadingeka kuphela ukukhululeka kobuhlungu kanye / noma ukususwa kokuvuvukala.