U-Androgens - iqembu lama-hormone ocansi, okhiqizwa kokubili owesilisa nomzimba wesifazane. Kodwa babhekwa njengabantu besilisa, ngoba ngaphansi kwethonya labo kukhona ukwakheka kwezici zobunikazi zesibili ngokohlobo lwesilisa. Emzimbeni wesifazane, ama-androgens angu-80% asezindaweni ezihambelanayo, ezingasebenzi. Kodwa esinye sezifo ezivame kakhulu zesistimu ye-endocrine - i- hyperandrogenism - yi-androgens engaphezu kwebesifazane. Kubangela ukukhathazeka okuningi esimweni sempilo futhi kubangelwa izizathu ezahlukene.
Ngokuvamile, ukuhlaziywa kwe-androgens kwabesifazane akubonakali ukwanda kwezinga labo egazini, futhi lesi sifo sibangelwa kulokhu ngokuphula umthetho wokubopha amahomoni aneprothemikhali ekhethekile kanye nokuhluleka kokubola kwe-androgen nokukhishwa kwabo emzimbeni. Lokhu kubangelwa kakhulu ngenxa yezifo zofuzo kanye nokukhiqizwa okungaziphathi kahle kwe-enzyme ethile.
Izimpawu ze-androgens ngokweqile kwabesifazane
Izimpawu ze-hyperandrogenism kwabesifazane:
- i-hirsutism, noma izinwele zokukhula kohlobo lwesilisa - ukugqugquzela izinwele ze-androgenic izinwele ziholela ekukhuleni kwezinwele ezimnyama ebusweni ebusweni, esiswini noma esifubeni;
- i-acne, i-seborrhea kanye nezinye izinkinga zesikhumba kubangelwa umsebenzi oweqile wezingqungquthela ezisabekayo ngaphansi kwethonya lamahomoni wesilisa omzimba;
- ukulahlekelwa izinwele kanye ne-alopecia kuyadingeka ebunzini;
- kwehla nge-timbre yezwi;
- izifo ezingcolile ezibangelwa izinga eliphezulu lama-androgens kwabesifazane ngokuvamile zibangelwa ukuphazamiseka kwengqondo, ukuzihlukanisa nokucindezeleka;
- ukuphazamiseka kwegazi, isibonelo, ama-ovaries we-polycystic, i-amenorrhea, ukungabi nabantwana kanye ne- endometrial hyperplasia ;
- ukwephula ibhalansi ye-hormonal kubangela izinkinga ze-endocrine futhi kungaholela ekubukeni kwesifo sikashukela, ukukhuluphala ngokweqile kanye ne-lipid metabolism.
Ukwelashwa kwe-hyperandrogenism
Ukuze ukwazi ukunciphisa i-androgens kowesifazane, udokotela kufanele ahlole ngokugcwele futhi abone imbangela yalesi simo. Phela, kungabangelwa ukwephulwa kwemisebenzi yesibindi, ukuntuleka kwe-vitamin noma ukuphathwa kwezidakamizwa ezithile,
Kodwa eminyakeni yamuva, ososayensi bathole ukuthi kuyingozi hhayi nje ukwandisa, kodwa futhi ukungabi nabanikazi be-androgens kwabesifazane. Lesi simo singabangela izifo zenhliziyo, ukuthuthukiswa kwe-osteoporosis nokuncipha ezingeni lika-hemoglobin. Ngakho-ke, kuhle kakhulu uma ama-hormone egazini ejwayelekile.