Ukuze uthole amaqanda alungele ukukhulelwa, kwenziwa amalungiselelo akhethekile okuvuselela ama-ovari. Inhlanganisela yale mithi ingahluka. Izinhlanganisela ezinjalo zibizwa ngokuthi izivumelwano. Ngokuvamile ku-fertilizer in vitro, izinhlobo ezimbili zezivumelwano zisetshenziswa. Lena yindlela ede futhi emfushane ye-IVF. Basebenzisa izidakamizwa ezifanayo. Inqubo emifushane ihluke kakhulu kumanani amancane kanye nesikhathi sokusebenza. Ukuze unqume ukuthi yiyiphi inqubo yokusebenza, udokotela uhlola ngokucophelela umlando wezokwelapha isiguli. Ibuye ibheke iminyaka, isisindo, isimo sesistimu yokuzala. Cabanga ukusetshenziswa kwamaprotheni ngesibonelo se-protocol emfushane IVF.
Isicelo kanye nobude besikhathi esifushane se-IVF protocol
Abesifazane abaningi abaxazulula izinkinga zokukhulelwa ngale ndlela, banesithakazelo sokuthi isikhathi esilandelayo sizoqhubeka kanjani. Ngokuyinhloko, iphrothotholi emifushane cishe ifana nomjikelezo wemvelo. Kuhlala amasonto amane, kanti isikhathi eside singamaviki ayisithupha. Lolu hlobo lwenqubo yokusebenzisa lusetshenzisiwe uma owesifazane enempendulo engafanele ye-ovarian kumjikelezo odlule we-protocol ende. Isibonakaliso sokusetshenziswa sineminyaka yobudala. Uma owesifazane ekhulile kuneminyaka ephakanyisiwe ekukhulisweni kwe-in vitro, kusetshenziswe iphrothotholi emifushane.
Izici ezihlukile zephrothokholi emifushane
Umehluko omkhulu phakathi kwenqubo emfushane neyesikhathi eside ukuthi, nge-protocol emfushane, isiguli ngokushesha siya esikhungweni esishukumisayo, kanti ngesikhathi eside kunesigaba esilandelayo. Ngokujwayelekile isigaba sokuvuselela siqala ngosuku lwesithathu lomjikelezo. Ngalesi sikhathi, isiguli siyeza ukuhlola, sidlula ukuhlolwa kwegazi. Ngesikhathi esifanayo, udokotela uqhuba ucwaningo ukuze aqiniseke ukuthi izicubu zesisu seziye zaba mncane ngemva kokuya esikhathini.
I-subspecies ye-IVF protocol emfushane kanye nobude bezinyathelo zokulandela
Kuye ngokuthi yiziphi izidakamizwa ezisetshenzisiwe, kukhona okufutshane ngama-agonists, okufutshane nabamelene naso futhi i-ultra-short ne-antagonists protocol.
Mfushane nama-agonists, i-GnRH ihlanganisa izigaba eziyisithupha eziyinhloko. Isigaba sokuqala ukuvinjelwa kwengcindezi ye-pituitary. Lesi sigaba sithatha kusukela ngosuku lwesithathu lomjikelezo kuya ekugqibeleni. Isebenzisa amalungiselelo anjalo we-protocol emfushane njenge-agonists GnRH, dexamethasone, folic acid. Ukukhuthazwa kuqala ngezinsuku ezingu-3-5 zomjikelezo bese kuqhubeka izinsuku ezingu-15-17. Bese kulandela ukukhishwa. Kuyenziwe izinsuku ezingu-14-20 emva kokuqala kokugqugquzela. Izinsuku ezingu-3-4 emva kokudluliswa kwesikhashana. Isigaba esilandelayo yisisekelo. Emva kokudluliselwa ngosuku lweshumi nane, ukulawula ukukhulelwa kwenziwa. Ngokuphelele, le protocol yabamba izinsuku ezingu-28-35. Ukungahambi kahle kwe-protocol ukuvota okuzenzakalelayo, izinga eliphansi lama-oocyte. I-plus ukuthi lokhu kudluliselwa kalula.
Okufushane (okufushane okuncane) nabantu abaphikisanayo banamaphesenti afanayo afushane nama-agonists, kuphela ngaphandle kwesiteji sokuvinjelwa kwengubo ye-pituitary.
Kukhona umqondo onjalo njengeprothotho ngaphandle kwama-analogues we-gonadoliberin (ahlanzekile). Kwezinye izimo, amasu angabandakanyi ukuvimbela i-pituitary gland asetshenzisiwe. Kulesi simo, kuphela amalungiselelo aqukethe i-FSH angasetshenziswa. Isibonelo,
Isici sephrothotholi emifushane
Uma usebenzisa le protocol, ukuvuthwa okuzenzakalelayo akunakwenzeka, njengoba izidakamizwa ezikhethekile zivimbela ukuphakama kwe-LH. Ngaphezu kwalokho, abesifazane babekezelela zonke izigaba ze-protocol. Futhi kukhona ukuvuselelwa okusheshayo komsebenzi we-pituitary gland. Umzimba womuntu awunamathele kancane ezintweni ezimbi futhi ingozi yokuthuthukisa i-cyst nale nqubo yanciphisa. I-protocol emfushane ihlala isikhathi esingaphansi futhi abesifazane bathola ukucindezeleka okungathí sina kwengqondo.