Ukuhlaziywa kwe-Chlamydia

I-Chlamydiosis urogenital yisifo esithathelwanayo esithwala kakhulu ngokuxhumana kocansi futhi sinikeza owesifazane izinkinga eziningi. Ku-10-15% wamacala inkambo yesifo isifihliwe, futhi owesifazane angase angasoli ukuthi utheleleke nge-chlamydia. Isidingo sokuhlaziywa kwe- chlamydia kwabesifazane singakhula uma sithola imbangela yokungasebenzi, ukukhulelwa kwe-ectopic noma ukukhipha isisu njalo. Sizozama ukucabangela ngokuningiliziwe ukuthi yiziphi izivivinyo ezibekwe i-chlamydia nokuthi zingayithatha kanjani.

Ziyaphi i-chlamydia?

Ukuhlaziywa kwegazi ku-chlamydia, igazi lisuka ku-vein lisetshenziswe, elisuswa isiguli esiswini esingenalutho. Kusukela egazini legazi, lezi zindlela ezilandelayo zingasetshenziswa:

1. Ukuhlolwa kwegazi nge-ELISA (enzyme immunoassay). Ngosizo lwalo, ama-antibodies (IgA, IgM, IgG) anqunyelwe i-chlamydia. Ngokusho kwe-titer (inombolo) ye-antibodies ethile, kungenzeka ukuthi sinqume ukuthi yisiphi isigaba lesi sifo esitholakalayo (esiyinkimbinkimbi, esingapheliyo, sokukhululwa). Ama-antibodies kuya ku-chlamydia avela ngesonto lesibili ngemva kokuqala kwesifo.
2. I-RIF (ukusabela kwe-immunofluorescence) Ukuhlaziywa kwe-Chlamydia kungenye yezinto ezinembile kakhulu (kufika ku-80%). Ukunemba kwalolu cwaningo kuxhomeke ekusebenzeni kochwepheshe we-laboratory.
3. Ukuhlaziywa kwe- PCR (i-polymerase chain response) yi-analysis ecacile kakhulu ye-chlamydia. Umphumela wokuhlaziywa kusekelwe ekutholeni izindawo zezinto zokwelapha ze-chlamydia.

Ukuqinisekisa ukuxilongwa, udokotela angathatha isisu esibelethweni bese esebenzisa indlela ye-PCR ukuthola izinhlamvu ze-DNA okuqukethwe. Ukuhlaziywa okunjalo kwe-smear ku-chlamydia nakho kuyitadisha lokuhlolisisa ulwazi. Uma uhlola i-smear ngaphansi kwe-microscope, ukutheleleka kwe-chlamydial kungatholakala kuphela ku-10-15% wamacala.

Ukuhlaziywa kwama-urine ku-chlamydia akuvamile ukushiwo, futhi owesifazane uxwayiswa ukuba angazigezi futhi agijime amahora amabili ngaphambi kokuthatha uhlolo. Esikhathini sesampula somchamo, izifunda ze-nucleic acids (i-DNA ne-RNA) ye-chlamydia zizimisele.

Kumele futhi kubhekiswe ukuthi kukhona ukuhlolwa okusheshayo kwe-chlamydia, engathengwa ekhemisi. Noma kunjalo, ngenxa yokuqukethwe okuphansi kwelwazi, akutholakalanga isicelo esikhulu.

Ukuhlolwa kwegazi kwe-chlamydia - okulotshiwe

Ukumiswa kwezivivinyo ze-laboratory kuqhutshwa isazi se-laboratory esinekhono esebenzisa imishini ekhethekile kanye nama-reagents. Isiguli sinikezwa umphumela wokuhlaziywa kwe-chlamydia, lapho kunomphumela omuhle noma omubi okhethiwe, futhi uma kunokwenzeka (ELISA) neziqu ze-antibodies.

1. Esigabeni esilesi sifo, esasanda kuqalwa (izinsuku zokuqala ezingu-5 kusukela ekuqaleni kwesifo), i-Ig M yokuqala
2. Owesibini egazini lesiguli nge-chlamydia livela i-Ig A, bathi isifo siyaqhubeka.
3. Ig G ivela ngesonto lesithathu lesi sifo, esibonisa ukuthi lesi sifo sidlulile esigabeni esingapheli.
4. Ngokucindezeleka kwe-chlamydia egazini lika-wesifazane, indlela yokuzivikela nge-immune-enzyme izokwenza ukuthi i-Ig G ne-Ig M. ikhuphuke ngokukhazimulayo. Lapho kuhlolwa izinga le-immunoglobulins ngale ndlela yokuphenya, kungenzeka ukuba uhlole ukuphumelela kokwelashwa kwe-chlamydia.
5. Ezokwelapha, kusekhona into efana ne-antibody titer, okungukuthi, inani elithile kwingxenye ethile. Ngakho-ke, i-IgG titer esigabeni esiyingozi sesi sifo kuyoba yi-1: 100 - 1: 6400, futhi isigaba sokuthola kabusha 1:50.

Akufanelekile ukunikeza futhi ukuhumusha ukuhlaziywa ku-chlomidia kumfazi. Indlela efanele yokuxilongwa kanye nokwelashwa kwe-chlamydial isifo kuphela udokotela onolwazi. Umsebenti wesifazane ngokwawo ukukhomba izimpawu zomzimba emzimbeni futhi ngokushesha ufune usizo lwezokwelapha.