I-Ursosan ingumuthi okhishwa eCzech Republic. I-group of pharmacotherapeutic ye-hepatoprotectors, ama-synthetic amalungiselelo we-bile acids. Le mithi iyakwazi ukuvikela amangqamuzana e-isibindi kusuka emiphumeleni ehlukahlukene embi futhi ikhulise isikhathi somsebenzi wabo wokusebenza ngenxa yezinto eziningi zokwelapha. Ake sicabangele ngokuningiliziwe ukuthi kunconywa ukuthi usebenzise nokuthi kanjani umuthi wase-Ursosan usebenza, kanye nezifaniso zawo.
Ukwakhiwa nomphumela wokwelapha wezidakamizwa ze-Ursosan
I-Ursosan itholakala ngesimo se-gelatin capsules, ehlanganisiwe ku-10, 50 no-100 izingcezu. Into esebenzayo yalesi sidakamizwa i-ursodeoxycholic acid. Le asidi iyinxenye engokwemvelo ye-bhala yomuntu, ngoba umuthi itholakala ngokuzenzekelayo. Indlela yokwenza umsebenzi osebenzayo wase-Ursosana isekelwe ekutheni uzinze amaseli wesibindi - ama-hepatocyte - futhi abenze banamathele amaningi emathonyeni ahlukahlukene. Ama-molecule we-ursodeoxycholic acid afakwa emgqeni wezingqimba zesibindi bese enza izakhiwo eziphephile nge-bile acids, enomthelela onobuthi, ngaleyo ndlela iwaqede.
Ngaphezu kwalokho, lesi sidakamizwa sinemiphumela elandelayo yokwelapha:
- isenzo se-choleretic (ukwanda kwe-bhala okwandisiwe nokusebenza kwe-excretion yayo);
- ukuvinjelwa kwemfundo kanye nokubhujiswa kwamatshe e-biliary cholesterol;
- ukwehla kwe- cholesterol egazini ;
- ukuqinisa isimiso somzimba;
- isithiyo ekuthuthukiseni izicubu ezinamafutha (isibindi) esiqandisini.
Ukungena emzimbeni womuntu, i-Ursosan ingene emathunjini amancane. Ukugxila okuphezulu kwegazi kugcinwa amahora amathathu emva kokuthatha lesi sidakamizwa. Ukusetshenziswa njalo kwalesi sidakamizwa kunomthelela ekwenzeni ukuthi u-ursodeoxycholic acid iba yi-acid enkulu ebhodini emzimbeni.
Izinkomba zokusetshenziswa kwe-Ursosan nezifanekiselo zayo
Izifo eziyinhloko eziphakamisa ukusetshenziswa kwezidakamizwa yizi:
- ukutholakala kwezitshalo kwi-gallbladder, okuyinhloko eyinhloko ye-cholesterol (ubukhulu bamatshe akufanele budlule ngo-15 mm ububanzi, futhi i-gallbladder kufanele isebenze);
- i-gastritis ene-reflux ye-bile;
- i-cirrhosis eyinhloko ye-biliary yesibindi (ngokungabikho kwezimpawu ze-decompensation).
Futhi, isidakamizwa sinconywa ngezifo ezinjalo:
- i-hepatitis engapheli yemvelaphi ehlukile;
- isifo sesibindi sesidakwa;
- i-dyskinesia ye-biliary ;
- i-cystic fibrosis;
- i-helminthiasis engapheli ebangelwa i-biotope ye-feline;
- ukulimala kwesibindi sobuthi, njll.
Yini engayenza esikhundleni se-Ursosan?
Uhlu lwamathebhulethi afanayo (ama-capsules) e-Ursosan, afaka phakathi i-ursodeoxycholic njenge-isithako esebenzayo, inkulu kakhulu. Ake sibhale kuqala izidakamizwa eziyinhloko ezikhiqizwa izinkampani zokwelapha zaseRussia:
- I-Urdok;
- I-ursodeoxycholic acid;
- I-Ursodez;
- Eshol.
Ama-analogues e-Ursosan, akhiqizwa ngabakhiqizi bangaphandle bemithi, yilezi:
- I-Livedoksa (i-India);
- I-Ursodex (i-India);
- I-Ursoliv (i-Thailand);
- I-Ursoron Rompharm (eRomania);
- I-Ursofalk (eJalimane);
- U-Ursohol (Ukraine) nabanye.
Ukuqhathaniswa kwe-Ursosan nokufana kwayo
U-Ursosan, kanye nalabo abathintekayo bakhe, bayaphikisana ngokuthatha izimo ezinjalo:
- amatshe e-gallbladder enokuqukethwe okuphezulu kwe-calcium;
- ukungasebenzi okwenziwe nge-gallbladder;
- i-cirrhosis yesibindi esigabeni sokuqedela;
- ukuvinjelwa kwepheshana le-biliary;
- ukutheleleka kwe-gallbladder ne-bile ducts esigabeni esiyingozi;
- ukuvuvukala okukhulu kwe-gallbladder;
- ukuqhwaba noma ukungafinyeleli kahle, njll.