I-AMG-hormone (i-antimulylerovskiy hormone) noma, njengoba ibizwa nangokuthi-into e-inhibitory ye-Muller, inesibopho sokuhlukanisa ubulili bombungu, ibandakanyeka ekuvuthweni kwe-follicle naku-spermatogenesis. Lesi sibonakaliso sisetshenziselwa ukucacisa izimbangela zokungabi nabesilisa nabesilisa , kanye nokutholakala kwezifo ezithile.
I-AMG yinto evamile kubesifazane
Kusukela ekubelethweni ukuya esikhathini sokuya esikhathini kwabesifazane, le hormone ikhiqizwa ngamangqamuzana angama-ovarie, futhi amazinga ayo aphezulu ahlonishwa ngamangqamuzana omzimba. I-AMG kwabesifazane ichazwa ukuze ibone ukuphuza isikhathi eside noma ngaphambi kwesikhathi sokubeletha, ukusungula ubulili, lapho lo mbuzo uphendulwa, lapho kutholakala i-granulosa cell carcinoma yama-ovarie nakwezinye izimo.
Ngaphezu kwalokho, i-antimulylerov hormone inconywa ukuba ilandele ukulungiselela i-IVF. Lokhu kuhlaziywa kwenziwa ngezinsuku ezithile zomjikelezo, kanti isilinganiso sokuthi i-inhibitor B kuya ezingeni le-AMN lihlolwa. Ku-IVF, izinga le-AMG-hormone kufanele libe okungenani 0.8 ng / ml.
Ngokuvamile, ngesikhathi sokuzala, ukuhlushwa kwe-AMG kwabesifazane kuvame ukuhlala ku-2.1-7.3 ng / ml. Uma izinga le-hormone liyehla ku-1.1 ng / ml futhi liphansi, umbuzo wokunciphisa indawo yokusebenza yama-ovari. Futhi ngokuncipha okubukhali kule ndawo yokugcina, amazinga ancishisiwe abe ngu-0.8 ng / ml futhi aphansi.
I-AMG ephansi ne-IVF
Ukunciphisa okunjalo ezingeni eliphansi le-AMG kusikisela ukuthi kungenzeka ukukhulelwa phakathi ne-IVF. Iziguli ezinezinsizakalo ezincishisiwe ezisebenzayo zama-ovari kanye nezinga le-anti-Muller le-hormone libhebhethekisa nakakhulu ekugqugquzelweni okwenziwa ezigabeni zokuqala zohlelo lokufaka umanyolo we-in vitro.
Ngaphezu kwalokho, izinga le-AMG ku-IVF lihlolwe ukuze lihlolwe ingozi yokuvuselela okunjalo ngokweqile. Ngezinye izikhathi le nqubo iholela esimweni esasongela ukuphila - isifo se-ovarian hyperstimulation. Njengoba unikeziwe lolu lwazi, ungaqhubeka uhlela uhlelo lokuphathwa kokungabi nabantwana.
Ungalungiselela kanjani ukuhlaziywa?
Ukuqhubeka nokulethwa kwe-AMG analysis kudingeka ulandele ezinye izincomo:
- Ungadli amahora angu-12 ngaphambi kwenqubo;
- Kubalulekile ukukhipha ngokuphelele ukungena kwe-androgens kungakapheli amahora angu-48 ngaphambi kokubelethwa kwegazi;
- ungabheki okungenani isigamu sehora ngaphambi kokuhlaziywa;
- Kunconywa ukuthi uqhube ukuhlaziywa ngosuku lwesithathu noma lwesine lwenyanga yokuya esikhathini.
Ukuze kuhlaziywe, owesifazane uthatha igazi eliyingozi, futhi indlela yokuphenya ngalolu daba iyinhlangano ye-enzyme immunoassay. Amayunithi wokulinganisa ama-nanograms nge-milliliter (ukuhlunga kwezinto ezisegazini kubalwa).