Zonke izinqubo zangaphakathi emzimbeni wanoma yimuphi umuntu zilawulwa amahomoni. Okubaluleke nakakhulu ama-hormone ocansi. Ngakho-ke, kubantu besifazane, ama-hormone obulili obuyinhloko yi-estrogens. Ukwehluleka kwabo noma ukugqithisa emzimbeni kuholela ekuthuthukiseni izinqubo zempilo. Ukuze kulungiswe isimo sesifazane, izidakamizwa ezine-hormone zivame ukusetshenziswa emithi. Ngakho-ke, namuhla i-estrogens iyatholakala ngendlela yamathebulethi.
Isetshenziswa nini?
Amathebulethi aqukethe i-estrogen, asetshenziswa njengenhloso yokwelapha, nokuvimbela ukukhulelwa. Inethiwekhi yekhemisi inikeza amalungiselelo amaningi nge-estrogen , athengiswa ngaphandle kwemithi. Naphezu kwalokhu, ngaphambi kokudliwa kwemithi ngayinye kubalulekile ukubonisana nodokotela wendawo, okuqeda ngokuphelele izingozi kanye nokuthuthukiswa kwemiphumela emibi.
Amalungiselelo aqukethe i-estrogen
Amalungiselelo okwelapha (amaphilisi), aqukethe i-hormone yesine estrogen, ingahlukaniswa ngamaqembu amabili: ukwelashwa nokukhulelwa.
Ngezinhloso zokwelapha, amaphilisi e-hormone aqukethe i-estrogen asetshenziswa uma:
- umjikelezo ongavamile wokuya esikhathini;
- ukuthuthukiswa kwezikhali zocansi zesifazane;
- ne-amenorrhea (ukuyeka esikhathini sokuya esikhathini);
- ubuthakathaka bokusebenza komsebenzi;
- ukungabikho.
Amaphilisi asetshenziswe kaningi, afaka i-hormone estrogen, yilezo zokubeletha ngomlomo kanye nokwelashwa kwe-hormone.
Ukukhulelwa komlomo
Isakhiwo samakhemikhali samaphilisi okukhulelwa namuhla aseduze ne-progesterone yemvelo nama-estrogen. Zonke izitho zomzimba ezikhona zomlomo ezikhona zihlukaniswe zibe yi-mono-, ezimbili, kanye nesigaba sesithathu. Indlela yokwenza lezi zidakamizwa kungenakwenzeka kwe-ovulation, ezuzwa ngokucindezela ukukhiqizwa kwama-hormone yi-pituitary ne-hypothalamus. Ama-hormone angena emzimbeni ngaphandle, ngakho-ke uyayeka ukuwahlanganisa. Amathebulethi aqukethe ama-estrogen awo asetshenziselwa ukuvimbela ukukhulelwa, lawa magama alandelayo:
- i-monophasic (i-Mersilon, i-Rigevidone, i-Diane-35);
- isigaba ezimbili (i-Antotevin);
- isigaba sesithathu (Tri-regol, Trikvilar, Triziston).
Le mithi yokwelapha ivame ukusetshenziselwa izinhloso zokwelapha. Ngakho-ke, ngemva kokuthatha le mithi, lo wesifazane anganciphisa inani legazi elinikezwe ngesikhathi sokuya esikhathini, ngesikhathi esifanayo - isifo sobuhlungu siyanyamalala. Ngenxa yalokho, ukuthatha le mithi kuholela esimisweni somjikelezo wokuya esikhathini.
Ukulungiswa kwe-hormone therapy esikhundleni
Amathebulethi aqukethe i-estrogen asetshenziselwa kakhulu ukuguqulwa kwama-hormone ocansi futhi asetshenziswa ngesikhathi sokuya esikhathini.
Kubo bonke abesifazane phakathi nenkathi yokumisa esikhathini sokuqala ukukhiqizwa kwama-hormone ezocansi kuncishiswe kakhulu. Yingakho udokotela akhetha amaphilisi okwandisa izinga le-estrogen. Yilezi zidakamizwa ezisiza ukubhekana nokubonakaliswa kokumisa esikhathini, futhi zisetshenziselwa ukwelashwa kwe-osteoporosis. Ngaphezu kwalokho, lezi zidakamizwa zingahle zivuselele izinga le-cholesterol emzimbeni,
Izidakamizwa ezisetshenziselwa ukwelashwa okunye okuqukethe i- estrogen ekumiseni kokumisa kufaka phakathi:
- kusho ukuphathwa ngomlomo (i-Estradiol valerate, i-Estradiol benzoate, i-Estradiol succinate);
- kusho ukusungulwa ngesikhumba (patch "Klimara");
- kusho umjovo (iGynodian Depot);
- kusho ukuphathwa kwebesifazane (amaphilisi e-vaginal ne-estrogen Ovestin).
Yonke imithi ehlongozwayo yabekwa udokotela futhi ithathwe ngaphansi kokuqondiswa kwayo kuphela.