Ukuphazamiseka kwegazi, ukwakheka nokuhlanganiswa kwamanzi kagesi kuqhubekisela phambili ukuthuthukiswa kwezifo ezihlukahlukene zezitho zangaphakathi nobuchopho, ngokuvamile kubangela ukuhlaselwa kwenhliziyo nokushaya. Ukuze kuxazululwe izinkinga ezinjalo, i-Trental ebiza kakhulu ivame ukubekwa - izifanekiselo zomuthi zingamanani aphansi, kodwa hhayi okuphumelelayo kangako.
Ngingayifaka kanjani i-Trental?
Ukuze ukhethe kahle i-analog, kubalulekile ukwazi ukubunjwa okuhambisana nokwenyuka kwesimo semithi.
Isithako esisebenzayo se-Trental yi-pentoxifylline-into eyanciphisa i-viscosity nobukhulu begazi, ivimbela ukukhiqizwa ngokweqile kwamaplatelets, iyanciphisa imithwalo yegazi. Ngenxa yalokhu umuthi uvumela ukuthuthukisa ukucwiliswa kwe-fluid eziphilayo ezicukheni ezithambile, ezihlanganisa ebuchosheni, ukuvimbela ukushaywa kwe-sclerotization kanye ne-thrombosis, ukuze kulungiswe izici ze-rheological zegazi.
Ngale ndlela, i-Trental ingashintshwa ngokugcwele kuphela ngezindlela ezakhiwe ngesisekelo se-pentoxifylline. Ngaphezu kwalokho, kudingeka uqaphele ukuhlushwa kwesithako esisebenzayo - 100 mg kanye no-400 mg (umphumela wesikhathi eside).
Ama-analogs omuthi we-Trental kumaphilisi
Esinye sezidakamizwa ezifanayo kakhulu ngu-Agapurin. Le mithi ikhiqizwa eSlovakia, kodwa isigaba samanani angabizi.
Ngokuthakazelisayo, ngaphezu kwesilinganiso se-ingredient esebenzayo esingu-100 no-400 mg, kukhona uhlobo olukhethekile lwe-Agapurin - I-Retard. Ukuhlushwa kwe-pentoxifylline kule ndlela yokukhululwa kufinyelele ku-600 mg, okwenza kube lula ukuphatha kahle ngisho nezifo ezinzima zezifo ezijikelezayo:
- ukuphika kwesifo sikashukela;
- ukuphefumula kwamathambo wezinto ezisebuchosheni;
- ukukhubazeka kokuzwa okusebenzayo ngenxa yezifo zamathambo;
- imiphumela ye-infarction ye-myocardial;
- ukuhlaselwa kwe-ischemic esiphezulu;
- i-endarteritis;
- ukuphazamiseka kwezidakamizwa;
- Isifo sikaRaynaud;
- ukungafinyeleleki okunamandla noma okungapheli kwegazi kule retina kanye negobolondo lamehlo.
Amanye ama-analogues aseTrental angama-200 no-400:
- I-Trenpental;
- I-Pentamon;
- I-Arbiflex;
- I-Ralofect;
- I-Pentylin no-Pentylin Forte;
- I-Vazonite;
- I-Radomine;
- IPentere;
- I-Flexitale;
- I-Pentohexal.
Kubalulekile ukuthi zonke lezi zidakamizwa zine-bioavailability ephezulu (cishe ngo-90%), okuqinisekisa ukugaya ngokushesha nokuphumelela kwemiphumela yokwelapha.
Okuthandwa kakhulu, okusebenzayo futhi ngesikhathi esifanayo nesifaniselo esingabizi kakhulu se-Trental yi-Pentoxifylline. Imithi iyingxenye ye-angioprotectors, eyenza imisebenzi elandelayo:
- ukuvinjelwa kwe-platelet aggregation;
- ukwehla kwe-viscosity yegazi;
- ukwandiswa kwemithambo yegazi nokuqinisa izindonga zabo, ukwanda kokuqina;
- ukuthuthukisa ukwenziwa kwamakhemikhali e-oksijini amathisula alula nesisindo;
- ukuqeda izimo ezibuhlungu kanye nesifo sobuhlungu emisipha ebangelwa ukuchotshozwa.
I-Pentoxifylline idedelwa emithini efanayo yemithi esebenzayo, uma kuziwa kwamathebulethi, njengoba izidakamizwa zichazwe.
Ama-analogues we-Trental ku-ampoules
Uma udinga ukunikeza izixazululo, kufanele ukhethe amagama alandelayo wemithi:
- I-Pentylin;
- I-Latren (ye-infusions);
- I-agapurin;
- Pentoxifylline.
Ukutholakala kwemithi yalezi zidakamizwa kuphezulu kakhulu-kufika ku-98%, ikakhulukazi ku-Agapurin. Njengomthetho, asetshenziselwa izinhlobo ezimbi zokusakaza kwe-cerebral, ukungaqondakali kwesifo sikashukela, kanye nokubuyisela isimo sesiguli ngemuva kokuhlaselwa yinhliziyo, ukuhlaselwa kwe-ischemic, ukushaya isifo .